| GWAS
|
| SNP
|
rs507666
|
| PubMedID
|
[PMID 18604267 ]
|
| Condition
|
Soluble ICAM-1
|
| Gene
|
ABO
|
| Risk Allele
|
G
|
| pValue
|
5.00E-029
|
| OR
|
17.73
|
| 95% CI
|
NR) umol/L decreas
|
| GWAS snp
|
| PMID
|
[PMID 21533024]
|
| Trait
|
|
| Title
|
Genome-wide association analysis of soluble ICAM-1 concentration reveals novel associations at the NFKBIK, PNPLA3, RELA, and SH2B3 loci.
|
| Risk Allele
|
A
|
| P-val
|
3E-91
|
| Odds Ratio
|
17.3000 [NR] ng/mL decrease
|
ABO blood group
[PMID 19474294] Potential etiologic and functional implications of genome-wide association loci for human diseases and traits.
[PMID 19648918] Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer.
rs507666, at the ABO (9q34.2) locus is highly correlated with sICAM-1 concentrations. The novel association at the ABO locus provides evidence for a previously unknown regulatory role of histo-blood group antigens in inflammatory adhesion processes.[18604267?dopt=Abstract PMID 18604267]
| GWAS snp
|
| PMID
|
[PMID 24386095]
|
| Trait
|
Lipid traits
|
| Title
|
A genome wide association study identifies common variants associated with lipid levels in the Chinese population.
|
| Risk Allele
|
A
|
| P-val
|
4E-11
|
| Odds Ratio
|
.02 [0.0091-0.0209] mmol/L increase
|
]
