rs5491
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 0 | common in complete genomics |
| Make rs5491(A;T) |
| Make rs5491(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 19 |
| Position | 10274864 |
| Gene | ICAM1, LOC105372272 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs5491 |
| dbSNP (classic) | rs5491 |
| ClinGen | rs5491 |
| ebi | rs5491 |
| HLI | rs5491 |
| Exac | rs5491 |
| Gnomad | rs5491 |
| Varsome | rs5491 |
| LitVar | rs5491 |
| Map | rs5491 |
| PheGenI | rs5491 |
| Biobank | rs5491 |
| 1000 genomes | rs5491 |
| hgdp | rs5491 |
| ensembl | rs5491 |
| geneview | rs5491 |
| scholar | rs5491 |
| rs5491 | |
| pharmgkb | rs5491 |
| gwascentral | rs5491 |
| openSNP | rs5491 |
| 23andMe | rs5491 |
| SNPshot | rs5491 |
| SNPdbe | rs5491 |
| MSV3d | rs5491 |
| GWAS Ctlg | rs5491 |
| GMAF | 0.07484 |
| Max Magnitude | 0 |
| ? | (A;A) (A;T) (T;T) | 28 |
|---|---|---|
|
| ||
[PMID 19332210
] Candidate genetic variants in the fibrinogen, methylenetetrahydrofolate reductase, and intercellular adhesion molecule-1 genes and plasma levels of fibrinogen, homocysteine, and intercellular adhesion molecule-1 among various race/ethnic groups: Data from the Women's Genome Health Study
[PMID 18420209] ICAM1 and VCAM1 polymorphisms, coronary artery calcium, and circulating levels of soluble ICAM-1: the multi-ethnic study of atherosclerosis (MESA)
[PMID 21392767] Polymorphisms in the ICAM1 gene predict circulating soluble intercellular adhesion molecule-1(sICAM-1)
| ClinVar | |
|---|---|
| Risk | rs5491(G;G) rs5491(T;T) |
| Alt | rs5491(G;G) rs5491(T;T) |
| Reference | Rs5491(A;A) |
| Significance | Other |
| Disease | Malaria |
| Variation | info |
| Gene | ICAM1 |
| CLNDBN | Malaria, cerebral, susceptibility to |
| Reversed | 0 |
| HGVS | NC_000019.9:g.10385540A>T |
| CLNSRC | OMIM Allelic Variant UniProtKB (protein) |
| CLNACC | RCV000015768.3, |
[PMID 15726497] Gene-environment interaction effects on the development of immune responses in the 1st year of life.
[PMID 16625213] ICAM1 amino-acid variant K469E is associated with paediatric bronchial asthma and elevated sICAM1 levels.
[PMID 16642433] Polymorphism in maternal LRP8 gene is associated with fetal growth.
[PMID 17327408] Prognostic significance of host immune gene polymorphisms in follicular lymphoma survival.
[PMID 17668374] Combining evidence of natural selection with association analysis increases power to detect malaria-resistance variants.
[PMID 17903293] Genome-wide association with select biomarker traits in the Framingham Heart Study.
[PMID 18045607] Circulating soluble ICAM-1 levels shows linkage to ICAM gene cluster region on chromosome 19: the NHLBI Family Heart Study follow-up examination.
[PMID 18528404] Variation in the ICAM1 gene is not associated with severe malaria phenotypes.
[PMID 18604267] Novel association of ABO histo-blood group antigen with soluble ICAM-1: results of a genome-wide association study of 6,578 women.
[PMID 18633131] Host immune gene polymorphisms in combination with clinical and demographic factors predict late survival in diffuse large B-cell lymphoma patients in the pre-rituximab era.
[PMID 19055786] Variations in host genes encoding adhesion molecules and susceptibility to falciparum malaria in India.
[PMID 19066394] Organochlorine exposure, immune gene variation, and risk of non-Hodgkin lymphoma.
[PMID 19131662] A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients.
[PMID 19330901] Association of 77 polymorphisms in 52 candidate genes with blood pressure progression and incident hypertension: the Women's Genome Health Study.
[PMID 19559392] A candidate gene association study of 77 polymorphisms in migraine.
[PMID 20031567] An evaluation of candidate genes of inflammation and thrombosis in relation to the risk of venous thromboembolism: The Women's Genome Health Study.
[PMID 20494378] Association between functional variants of the ICAM1 and CRP genes and metabolic syndrome in Taiwanese subjects.
[PMID 23114149] [Effects of ICAM-1 Gene K469E, K56M Polymorphisms on Plasma sICAM-1 Expression Levels in Chinese Yugur, Tibetan and Han Nationalities]
[PMID 24069166] Combined effects of icam-1 single-nucleotide polymorphisms and environmental carcinogens on oral cancer susceptibility and clinicopathologic development
[PMID 24955718] Interaction of Intercellular Adhesion Molecule 1 (ICAM1) Polymorphisms and Environmental Tobacco Smoke on Childhood Asthma
[PMID 25003170] Interaction of intercellular adhesion molecule 1 (ICAM1) polymorphisms and environmental tobacco smoke on childhood asthma
[PMID 26078712] Impact of Intercellular Adhesion Molecule-1 Genetic Polymorphisms on Coronary Artery Disease Susceptibility in Taiwanese Subjects
[PMID 26341495] Association of intercellular adhesion molecule-1 single nucleotide polymorphisms with hepatocellular carcinoma susceptibility and clinicopathologic development
[PMID 26377999] Single-Nucleotide Polymorphisms and Haplotypes of Intercellular Adhesion Molecule-1 in Uterine Cervical Carcinogenesis in Taiwanese Women
