rs56038477
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | common/normal |
| (C;T) | 2 | Carrier of a decreased function DPYD gene allele |
| (T;T) | 3.5 | Likely toxicity if treated with certain fluoropyrimidine-based chemotherapeutics |
| is a | snp |
| is | mentioned by |
| dbSNP | rs56038477 |
| dbSNP (classic) | rs56038477 |
| ClinGen | rs56038477 |
| ebi | rs56038477 |
| HLI | rs56038477 |
| Exac | rs56038477 |
| Gnomad | rs56038477 |
| Varsome | rs56038477 |
| LitVar | rs56038477 |
| Map | rs56038477 |
| PheGenI | rs56038477 |
| Biobank | rs56038477 |
| 1000 genomes | rs56038477 |
| hgdp | rs56038477 |
| ensembl | rs56038477 |
| geneview | rs56038477 |
| scholar | rs56038477 |
| rs56038477 | |
| pharmgkb | rs56038477 |
| gwascentral | rs56038477 |
| openSNP | rs56038477 |
| 23andMe | rs56038477 |
| SNPshot | rs56038477 |
| SNPdbe | rs56038477 |
| MSV3d | rs56038477 |
| GWAS Ctlg | rs56038477 |
| Max Magnitude | 3.5 |
aka c.1236G>A (p.Glu412= or 412E); decreased function DPYD gene allele
PharmGKB notes that cancer patients carrying a rs56038477(T) allele treated with fluoropyrimidine-based chemotherapy may have an increased risk for drug toxicities as compared to patients with the (C;C) genotype.
