rs5743618
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (G;G) | 2 | greater resistance to leprosy; but also consequence for Lyme patients |
| Make rs5743618(G;T) |
| Make rs5743618(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 4 |
| Position | 38797027 |
| Gene | TLR1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs5743618 |
| dbSNP (classic) | rs5743618 |
| ClinGen | rs5743618 |
| ebi | rs5743618 |
| HLI | rs5743618 |
| Exac | rs5743618 |
| Gnomad | rs5743618 |
| Varsome | rs5743618 |
| LitVar | rs5743618 |
| Map | rs5743618 |
| PheGenI | rs5743618 |
| Biobank | rs5743618 |
| 1000 genomes | rs5743618 |
| hgdp | rs5743618 |
| ensembl | rs5743618 |
| geneview | rs5743618 |
| scholar | rs5743618 |
| rs5743618 | |
| pharmgkb | rs5743618 |
| gwascentral | rs5743618 |
| openSNP | rs5743618 |
| 23andMe | rs5743618 |
| SNPshot | rs5743618 |
| SNPdbe | rs5743618 |
| MSV3d | rs5743618 |
| GWAS Ctlg | rs5743618 |
| GMAF | 0.331 |
| Max Magnitude | 2 |
[PMID 22238472
] Variants in toll-like receptor 1 and 4 genes are associated with Chlamydia trachomatis among women with pelvic inflammatory disease
| ClinVar | |
|---|---|
| Risk | rs5743618(T;T) |
| Alt | rs5743618(T;T) |
| Reference | Rs5743618(G;G) |
| Significance | Other |
| Disease | Leprosy |
| Variation | info |
| Gene | TLR1 |
| CLNDBN | Leprosy, protection against |
| Reversed | 1 |
| HGVS | NC_000004.11:g.38798648C>A |
| CLNSRC | OMIM Allelic Variant UniProtKB (protein) |
| CLNACC | RCV000008865.5, |
[PMID 18396467] Genetic variation and haplotype structures of innate immunity genes in eastern India.
[PMID 18635889] Toll-like receptor 1 polymorphisms affect innate immune responses and outcomes in sepsis.
[PMID 19134200] No evidence of major effects in several Toll-like receptor gene polymorphisms in rheumatoid arthritis.
[PMID 19543401] Toll-like receptor polymorphisms and susceptibility to urinary tract infections in adult women.
[PMID 20016852] Genetic variation of the human urinary tract innate immune response and asymptomatic bacteriuria in women.
[PMID 20478407] The toll-like receptor 1 variant S248N influences placental malaria.
[PMID 20617178] Leprosy and the adaptation of human toll-like receptor 1.
[PMID 21872627] Association of polymorphisms in TLR genes and in genes of the Toll-like receptor signaling pathway with cancer risk.
[PMID 23255565] Racial variation in toll-like receptor variants among women with pelvic inflammatory disease.
