rs5744168
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | common in complete genomics |
| (G;G) | 0 |
| Make rs5744168(C;T) |
| Make rs5744168(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 1 |
| Position | 223111858 |
| Gene | TLR5 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs5744168 |
| dbSNP (classic) | rs5744168 |
| ClinGen | rs5744168 |
| ebi | rs5744168 |
| HLI | rs5744168 |
| Exac | rs5744168 |
| Gnomad | rs5744168 |
| Varsome | rs5744168 |
| LitVar | rs5744168 |
| Map | rs5744168 |
| PheGenI | rs5744168 |
| Biobank | rs5744168 |
| 1000 genomes | rs5744168 |
| hgdp | rs5744168 |
| ensembl | rs5744168 |
| geneview | rs5744168 |
| scholar | rs5744168 |
| rs5744168 | |
| pharmgkb | rs5744168 |
| gwascentral | rs5744168 |
| openSNP | rs5744168 |
| 23andMe | rs5744168 |
| SNPshot | rs5744168 |
| SNPdbe | rs5744168 |
| MSV3d | rs5744168 |
| GWAS Ctlg | rs5744168 |
| GMAF | 0.03994 |
| Max Magnitude | 0 |
[PMID 19473567] Investigation of TLR5 and TLR7 as candidate genes for susceptibility to systemic lupus erythematosus
[PMID 21068401] TLR5 as an Anti-Inflammatory Target and Modifier Gene in Cystic Fibrosis
[PMID 21494356
] Association of Toll-Like Receptor 5 Gene Polymorphism with Susceptibility to Ossification of the Posterior Longitudinal Ligament of the Spine in Korean Population
| ClinVar | |
|---|---|
| Risk | rs5744168(T;T) |
| Alt | rs5744168(T;T) |
| Reference | Rs5744168(C;C) |
| Significance | Other |
| Disease | Legionellosis Systemic lupus erythematosus Melioidosis |
| Variation | info |
| Gene | TLR5 |
| CLNDBN | Legionellosis Systemic lupus erythematosus, resistance to, 1 Melioidosis, resistance to |
| Reversed | 1 |
| HGVS | NC_000001.10:g.223285200G>A |
| CLNSRC | OMIM Allelic Variant |
| CLNACC | RCV000007037.5, RCV000007038.6, RCV000074501.6, |
[PMID 16846490] Lemierre's syndrome and genetic polymorphisms: a case report.
[PMID 17516623] Association study of Toll-like receptor 5 (TLR5) and Toll-like receptor 9 (TLR9) polymorphisms in systemic lupus erythematosus.
[PMID 18396467] Genetic variation and haplotype structures of innate immunity genes in eastern India.
[PMID 18635889] Toll-like receptor 1 polymorphisms affect innate immune responses and outcomes in sepsis.
[PMID 19543401] Toll-like receptor polymorphisms and susceptibility to urinary tract infections in adult women.
[PMID 19838195] A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.
[PMID 20016852] Genetic variation of the human urinary tract innate immune response and asymptomatic bacteriuria in women.
[PMID 21872627] Association of polymorphisms in TLR genes and in genes of the Toll-like receptor signaling pathway with cancer risk.
[PMID 23447684] Impaired TLR5 functionality is associated with survival in melioidosis.
[PMID 23455496] A nonsense polymorphism (R392X) in TLR5 protects from obesity but predisposes to diabetes.
[PMID 23526294] Polymorphisms in toll-like receptors 2, 4 and 5 are associated with Legionella pneumophila infection.
[PMID 25807366] Urinary Proteins, Vitamin D and Genetic Polymorphisms as Risk Factors for Febrile Urinary Tract Infection and Relation with Bacteremia: A Case Control Study
[PMID 29179462] Toll-like receptor 5 gene polymorphism is associated with breast cancer susceptibility.
