rs579459

Orientation

plus

Stabilized

plus

Make rs579459(C;C)

Make rs579459(C;T)

Make rs579459(T;T)

Reference

GRCh38 38.1/141

Chromosome

9

Position

133278724

is a	snp
is	mentioned by
dbSNP	rs579459
dbSNP (classic)	rs579459
ClinGen	rs579459
ebi	rs579459
HLI	rs579459
Exac	rs579459
Gnomad	rs579459
Varsome	rs579459
LitVar	rs579459
Map	rs579459
PheGenI	rs579459
Biobank	rs579459
1000 genomes	rs579459
hgdp	rs579459
ensembl	rs579459
geneview	rs579459
scholar	rs579459
google	rs579459
pharmgkb	rs579459
gwascentral	rs579459
openSNP	rs579459
23andMe	rs579459
SNPshot	rs579459
SNPdbe	rs579459
MSV3d	rs579459
GWAS Ctlg	rs579459

GMAF

0.1887

Max Magnitude

0

?	(C;C) (C;T) (T;T)	28

GWAS snp
PMID	[PMID 19729612]
Trait	Serum soluble E-selectin
Title	Genome-Wide Association Identifies the ABO Blood Group as a Major Locus Associated With Serum Levels of Soluble E-Selectin
Risk Allele	C
P-val	1E-29
Odds Ratio	NR NR

GWAS snp
PMID	[PMID 20167578]
Trait	Soluble levels of adhesion molecules
Title	Large-scale genomic studies reveal central role of ABO in sP-selectin and sICAM-1 levels
Risk Allele	T
P-val	2E-41
Odds Ratio	14.00 [12.04-15.96] % increase

GWAS snp
PMID	[PMID 21378990]
Trait
Title	Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
Risk Allele	C
P-val	4E-14
Odds Ratio	1.1000 [1.07-1.13]

[PMID 22010135] Association of Variation at the ABO Locus with Circulating Levels of sICAM-1, sP-selectin and sE-selectin: A Meta-Analysis

GWAS snp
PMID	[PMID 22001757]
Trait
Title	Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.
Risk Allele	T
P-val	3E-123
Odds Ratio	8.8000 None

Coronary Heart Disease

GWAS snp
PMID	[PMID 23222517]
Trait	Red blood cell traits
Title	Seventy-five genetic loci influencing the human red blood cell.
Risk Allele	T
P-val	9E-18
Odds Ratio	.02 [0.015-0.027] unit increase

[PMID 23161703] Influence of 23 coronary artery disease variants on recurrent myocardial infarction or cardiac death: the GRACE Genetics Study.

GWAS snp
PMID	[PMID 24262325]
Trait	Coronary artery disease
Title	Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.
Risk Allele	C
P-val	2E-7
Odds Ratio	1.10 [1.06-1.14]

GWAS snp
PMID	[PMID 24586186]
Trait	Urinary metabolites (H-NMR features)
Title	Genome-wide association study of metabolic traits reveals novel gene-metabolite-disease links.
Risk Allele	T
P-val	1E-28
Odds Ratio	.49 [NR] unit increase

GWAS snp
PMID	[PMID 24816252]
Trait	Blood metabolite ratios
Title	An atlas of genetic influences on human blood metabolites.
Risk Allele	T
P-val	1E-28
Odds Ratio	.12 [0.1-0.15] unit decrease

[PMID 24251769] LDL-c-linked SNPs are associated with LDL-c and myocardial infarction despite lipid-lowering therapy in patients with established vascular disease

[PMID 26413716] A GWAS Study on Liver Function Test Using eMERGE Network Participants

[PMID 29390587] Prospective association of a genetic risk score with major adverse cardiovascular events in patients with coronary artery disease.