rs588765
| Orientation | plus |
| Stabilized | plus |
| Make rs588765(C;C) |
| Make rs588765(C;T) |
| Make rs588765(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 15 |
| Position | 78573083 |
| Gene | CHRNA5 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs588765 |
| dbSNP (classic) | rs588765 |
| ClinGen | rs588765 |
| ebi | rs588765 |
| HLI | rs588765 |
| Exac | rs588765 |
| Gnomad | rs588765 |
| Varsome | rs588765 |
| LitVar | rs588765 |
| Map | rs588765 |
| PheGenI | rs588765 |
| Biobank | rs588765 |
| 1000 genomes | rs588765 |
| hgdp | rs588765 |
| ensembl | rs588765 |
| geneview | rs588765 |
| scholar | rs588765 |
| rs588765 | |
| pharmgkb | rs588765 |
| gwascentral | rs588765 |
| openSNP | rs588765 |
| 23andMe | rs588765 |
| SNPshot | rs588765 |
| SNPdbe | rs588765 |
| MSV3d | rs588765 |
| GWAS Ctlg | rs588765 |
| GMAF | 0.2759 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
[PMID 19706806] A Novel Polymorphism rs1329149 of CYP2E1 and a Known Polymorphism rs671 of ALDH2 of Alcohol Metabolizing Enzymes Are Associated with Colorectal Cancer in a Southwestern Chinese Population
[PMID 19706810] Variants Weakly Correlated with CHRNA5 D398N Polymorphism Should be Considered in Transcriptional Deregulation at the 15q25 Locus Associated with Lung Cancer Risk
[PMID 20700436
] Multiple Independent Loci at Chromosome 15q25.1 Affect Smoking Quantity: a Meta-Analysis and Comparison with Lung Cancer and COPD
| OMIM | 118505 |
| Desc | CHOLINERGIC RECEPTOR, NEURONAL NICOTINIC, ALPHA POLYPEPTIDE 5; CHRNA5 |
| Variant | |
| Related | also |
[PMID 19029397] Nicotinic receptor gene variants influence susceptibility to heavy smoking.
[PMID 19443489] Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5.
[PMID 19706762] The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans.
[PMID 23249876] Nicotinic acetylcholine receptor variation and response to smoking cessation therapies
[PMID 22884254] Association of nicotine dependence susceptibility gene, CHRNA5, with Parkinson's disease age at onset: gene and smoking status interaction.
[PMID 23011884] Functional effect of polymorphisms in 15q25 locus on CHRNA5 mRNA, bulky DNA adducts and TP53 mutations.
[PMID 23404318] Interpreting joint SNP analysis results: when are two distinct signals really two distinct signals?
[PMID 25632390] Association between genetic variants on chromosome 15q25 locus and several nicotine dependence traits in Polish population: a case-control study
[PMID 29052254] Genetic polymorphisms associated with smoking behaviour predict the risk of surgery in patients with Crohn's disease.
[PMID 27197960] Association between variants in nicotinic acetylcholine receptor genes and smoking cessation in a Chinese rural population.
