rs58920878
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | common/normal |
| (C;G) | 2 | slight (~1.5x) increase in colorectal cancer risk |
| (G;G) | 2 | slight (~2x) increase in colorectal cancer risk |
| Reference | GRCh38 38.1/141 |
| Chromosome | 18 |
| Position | 48923195 |
| Gene | SMAD7 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs58920878 |
| dbSNP (classic) | rs58920878 |
| ClinGen | rs58920878 |
| ebi | rs58920878 |
| HLI | rs58920878 |
| Exac | rs58920878 |
| Gnomad | rs58920878 |
| Varsome | rs58920878 |
| LitVar | rs58920878 |
| Map | rs58920878 |
| PheGenI | rs58920878 |
| Biobank | rs58920878 |
| 1000 genomes | rs58920878 |
| hgdp | rs58920878 |
| ensembl | rs58920878 |
| geneview | rs58920878 |
| scholar | rs58920878 |
| rs58920878 | |
| pharmgkb | rs58920878 |
| gwascentral | rs58920878 |
| openSNP | rs58920878 |
| 23andMe | rs58920878 |
| SNPshot | rs58920878 |
| SNPdbe | rs58920878 |
| MSV3d | rs58920878 |
| GWAS Ctlg | rs58920878 |
| GMAF | 0.343 |
| Max Magnitude | 2 |
10.1038/ejhg.2015.72 rs58920878 on 18q21.1 (colorectal cancer OR 1.49, CI: 1.14–1.95, P=0.0035)
[PMID 24448986
] Genome-wide association study identifies a new SMAD7 risk variant associated with colorectal cancer risk in East Asians
[PMID 25375357] Multiple Functional Risk Variants in a SMAD7 Enhancer Implicate a Colorectal Cancer Risk Haplotype
[PMID 25873010] Clinical relevance of 8q23, 15q13 and 18q21 SNP genotyping to evaluate colorectal cancer risk
