11.4x higher risk of thrombosis |
Geno
|
Mag
|
Summary
|
(A;A)
|
7
|
11.4x higher risk of thrombosis
|
(A;G)
|
4.1
|
3.5-4.4x risk of thrombosis
|
(G;G)
|
0
|
normal/common risk of thrombosis
|
Significantly increased risk of thrombosis. The homozygous minor allele variant is very rare. Magnitude & Odds ratio is from a 2013 study, based on 116 subjects among cases and 24 controls. See discussion at rs6025.
Note: Independent risk for thrombosis was also seen in variants of the PT20210A or Factor 2 SNP at i3002432 (also known as rs1799963