rs610604
| Orientation | minus |
| Stabilized | minus |
| Make rs610604(A;A) |
| Make rs610604(A;C) |
| Make rs610604(C;C) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 6 |
| Position | 137878280 |
| Gene | TNFAIP3 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs610604 |
| dbSNP (classic) | rs610604 |
| ClinGen | rs610604 |
| ebi | rs610604 |
| HLI | rs610604 |
| Exac | rs610604 |
| Gnomad | rs610604 |
| Varsome | rs610604 |
| LitVar | rs610604 |
| Map | rs610604 |
| PheGenI | rs610604 |
| Biobank | rs610604 |
| 1000 genomes | rs610604 |
| hgdp | rs610604 |
| ensembl | rs610604 |
| geneview | rs610604 |
| scholar | rs610604 |
| rs610604 | |
| pharmgkb | rs610604 |
| gwascentral | rs610604 |
| openSNP | rs610604 |
| 23andMe | rs610604 |
| SNPshot | rs610604 |
| SNPdbe | rs610604 |
| MSV3d | rs610604 |
| GWAS Ctlg | rs610604 |
| GMAF | 0.3627 |
| Max Magnitude | 0 |
| ? | (A;A) (A;C) (C;C) | 28 |
|---|---|---|
|
| ||
23andMe blog psoriasis Europeans
- rs610604(G) 1.19x risk
| GWAS snp | |
|---|---|
| PMID | [PMID 19169254 ]
|
| Trait | Psoriasis |
| Title | Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways |
| Risk Allele | G |
| P-val | 9E-12 |
| Odds Ratio | 1.19 None |
| GWAS snp | |
|---|---|
| PMID | [PMID 20953190]
|
| Trait | |
| Title | A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1 |
| Risk Allele | |
| P-val | 7E-7 |
| Odds Ratio | 1.2200 [1.13-1.32] |
[PMID 21623003] Confirmation of TNIP1 and IL23A as susceptibility loci for psoriatic arthritis
[PMID 22113471] TNFAIP3 gene polymorphisms are associated with response to TNF blockade in psoriasis.
[PMID 17259397] Tag polymorphisms at the A20 (TNFAIP3) locus are associated with lower gene expression and increased risk of coronary artery disease in type 2 diabetes.
[PMID 19262574] Genome-wide association scan yields new insights into the immunopathogenesis of psoriasis.
[PMID 21253569] Genome-wide association study SNPs in the human genome diversity project populations: does selection affect unlinked SNPs with shared trait associations?
[PMID 23161053] TNFAIP3 gene polymorphisms confer risk for Behcet's disease in a Chinese Han population
[PMID 23521149] Pharmacogenetics of psoriasis: HLA-Cw6 but not LCE3B/3C deletion nor TNFAIP3 polymorphism predisposes to clinical response to interleukin 12/23 blocker ustekinumab.
[PMID 25496073] The TNFAIP3 polymorphism rs610604 both associates with the risk of psoriasis vulgaris and affects the clinical severity
[PMID 26005883] Lack of association of TNFAIP3 and JAK1 with Behçet's disease in the European population
