rs61761208
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 0 | common/normal |
| (A;T) | 8 | Early-onset Alzheimer's mutation (reported) |
| Make rs61761208(T;T) |
| Reference | GRCh38.p7 38.3/150 |
| Chromosome | 1 |
| Position | 226885602 |
| Gene | PSEN2 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs61761208 |
| dbSNP (classic) | rs61761208 |
| ClinGen | rs61761208 |
| ebi | rs61761208 |
| HLI | rs61761208 |
| Exac | rs61761208 |
| Gnomad | rs61761208 |
| Varsome | rs61761208 |
| LitVar | rs61761208 |
| Map | rs61761208 |
| PheGenI | rs61761208 |
| Biobank | rs61761208 |
| 1000 genomes | rs61761208 |
| hgdp | rs61761208 |
| ensembl | rs61761208 |
| geneview | rs61761208 |
| scholar | rs61761208 |
| rs61761208 | |
| pharmgkb | rs61761208 |
| gwascentral | rs61761208 |
| openSNP | rs61761208 |
| 23andMe | rs61761208 |
| SNPshot | rs61761208 |
| SNPdbe | rs61761208 |
| MSV3d | rs61761208 |
| GWAS Ctlg | rs61761208 |
| Max Magnitude | 8 |
rs61761208, also known as c.421A>T, N141Y or Asn141Tyr, is a mutation in the presenilin 2 PSEN2 gene.
The minor allele is reported as pathogenic for early-onset Alzheimer's disease in the AlzForum database, based on a 2014 publication.[PMID 24838186]
