Have questions? Visit https://www.reddit.com/r/SNPedia

rs61761208

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 0 common/normal
(A;T) 8 Early-onset Alzheimer's mutation (reported)
Make rs61761208(T;T)
ReferenceGRCh38.p7 38.3/150
Chromosome1
Position226885602
GenePSEN2
is asnp
is mentioned by
dbSNPrs61761208
dbSNP (classic)rs61761208
ClinGenrs61761208
ebirs61761208
HLIrs61761208
Exacrs61761208
Gnomadrs61761208
Varsomers61761208
LitVarrs61761208
Maprs61761208
PheGenIrs61761208
Biobankrs61761208
1000 genomesrs61761208
hgdprs61761208
ensemblrs61761208
geneviewrs61761208
scholarrs61761208
googlers61761208
pharmgkbrs61761208
gwascentralrs61761208
openSNPrs61761208
23andMers61761208
SNPshotrs61761208
SNPdbers61761208
MSV3drs61761208
GWAS Ctlgrs61761208
Max Magnitude8

rs61761208, also known as c.421A>T, N141Y or Asn141Tyr, is a mutation in the presenilin 2 PSEN2 gene.


The minor allele is reported as pathogenic for early-onset Alzheimer's disease in the AlzForum database, based on a 2014 publication.[PMID 24838186]