rs6413458

Orientation

minus

Stabilized

minus

Geno	Mag	Summary
(C;C)	0	common in clinvar

Make rs6413458(C;T)

Make rs6413458(T;T)

Reference

GRCh38 38.1/142

Chromosome

2

Position

21008720

Gene

APOB

is a	snp
is	mentioned by
dbSNP	rs6413458
dbSNP (classic)	rs6413458
ClinGen	rs6413458
ebi	rs6413458
HLI	rs6413458
Exac	rs6413458
Gnomad	rs6413458
Varsome	rs6413458
LitVar	rs6413458
Map	rs6413458
PheGenI	rs6413458
Biobank	rs6413458
1000 genomes	rs6413458
hgdp	rs6413458
ensembl	rs6413458
geneview	rs6413458
scholar	rs6413458
google	rs6413458
pharmgkb	rs6413458
gwascentral	rs6413458
openSNP	rs6413458
23andMe	rs6413458
SNPshot	rs6413458
SNPdbe	rs6413458
MSV3d	rs6413458
GWAS Ctlg	rs6413458

GMAF

0.01423

Max Magnitude

0

?	(C;C) (C;T) (T;T)	28

GWAS snp
PMID	[PMID 23118302]
Trait	Lipoprotein-associated phospholipase A2 activity and mass
Title	Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.
Risk Allele	T
P-val	2E-7
Odds Ratio	.04 [0.0088-0.0708] ng/ml decrease

ClinVar
Risk	rs6413458(T;T)
Alt	rs6413458(T;T)
Reference	Rs6413458(C;C)
Significance	Probable-non-pathogenic
Disease	Hypercholesterolemia Hypobetalipoproteinemia Familial hypercholesterolemia Familial hypobetalipoproteinemia not specified
Variation	info
Gene	APOB
CLNDBN	Hypercholesterolemia, autosomal dominant, type B Hypobetalipoproteinemia, familial, 1 Familial hypercholesterolemia Familial hypobetalipoproteinemia not specified
Reversed	1
HGVS	NC_000002.11:g.21231592G>A
CLNSRC
CLNACC	RCV000231970.2, RCV000296376.1, RCV000351344.1, RCV000441626.1,