news the presence of the G allele was protective against follicular lymphoma, while the presence of the A allele was predictive of an increased risk of developing follicular lymphoma. Dr. Brown said individuals who had the A variant were nearly twice as likely to develop follicular lymphoma.
23andMe blog coverage
| GWAS snp
|
| PMID
|
[PMID 19620980 ]
|
| Trait
|
Follicular lymphoma
|
| Title
|
Genetics variants at 6p21.33 are associated with susceptibility to follicular lymphoma
|
| Risk Allele
|
C
|
| P-val
|
5E-11
|
| Odds Ratio
|
1.69 [1.43-2.00]
|
| GWAS snp
|
| PMID
|
[PMID 20639881]
|
| Trait
|
Follicular lymphoma
|
| Title
|
Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32
|
| Risk Allele
|
C
|
| P-val
|
0.000007
|
| Odds Ratio
|
1.47 [1.27-1.72]
|
[PMID 21233317] SNP rs6457327 in the HLA region on chromosome 6p is predictive of the transformation of follicular lymphoma
[PMID 28139690] SNP variants associated with non-Hodgkin lymphoma (NHL) correlate with human leukocyte antigen (HLA) class II expression.
]
