| Geno
|
Mag
|
Summary
|
| (C;C)
|
|
<0.71x risk for restless legs
|
| (C;G)
|
|
0.71x risk for restless legs
|
| (G;G)
|
0
|
common
|
rs6494696, a SNP located in a region of chromosome 15q, has been linked to a lower frequency of restless legs syndrome, a common sleep disorder, with an overall odds ratio of 0.71 (CI: 0.60-0.83) for the (C) minor allele. [PMID 17637780]
The association between this SNP and RLS has been replicated in three European populations.[PMID 19279021
]
| OMIM | 102300 |
| Desc | RESTLESS LEGS SYNDROME, SUSCEPTIBILITY TO, 1 |
| Variant | |
| Related | also |
[PMID 25142570] Periodic leg movements during sleep are associated with polymorphisms in BTBD9, TOX3/BC034767, MEIS1, MAP2K5/SKOR1, and PTPRD
[PMID 28329290] Association of BTBD9 and MAP2K5/SKOR1 With Restless Legs Syndrome in Chinese Population.
]
