rs6548238
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 |
| Make rs6548238(C;T) |
| Make rs6548238(T;T) |
| Reference | GRCh37 37.1/131 |
| Chromosome | 2 |
| Position | 634905 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs6548238 |
| dbSNP (classic) | rs6548238 |
| ClinGen | rs6548238 |
| ebi | rs6548238 |
| HLI | rs6548238 |
| Exac | rs6548238 |
| Gnomad | rs6548238 |
| Varsome | rs6548238 |
| LitVar | rs6548238 |
| Map | rs6548238 |
| PheGenI | rs6548238 |
| Biobank | rs6548238 |
| 1000 genomes | rs6548238 |
| hgdp | rs6548238 |
| ensembl | rs6548238 |
| geneview | rs6548238 |
| scholar | rs6548238 |
| rs6548238 | |
| pharmgkb | rs6548238 |
| gwascentral | rs6548238 |
| openSNP | rs6548238 |
| 23andMe | rs6548238 |
| SNPshot | rs6548238 |
| SNPdbe | rs6548238 |
| MSV3d | rs6548238 |
| GWAS Ctlg | rs6548238 |
| GMAF | 0.1281 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
| GWAS snp | |
|---|---|
| PMID | [PMID 19079261 ]
|
| Trait | Body mass index |
| Title | Six new loci associated with body mass index highlight a neuronal influence on body weight regulation |
| Risk Allele | C |
| P-val | 1E-18 |
| Odds Ratio | 0.26 [0.19-0.34] kg/m2 increase |
[PMID 19851340] Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population
[PMID 20386550] Genes and lifestyle factors in obesity: results from 12 462 subjects from MONICA/KORA
[PMID 20380707] The obesity gene, TMEM18, is of ancient origin, found in majority of neuronal cells in all major brain regions and associated with obesity in severely obese children
[PMID 21796141] Computed tomography analysis of the association between the SH2B1 rs7498665 single-nucleotide polymorphism and visceral fat area
[PMID 22083549] Study of eight GWAS-identified common variants for association with obesity-related indices in Chinese children at puberty
[PMID 19164386] Replication and extension of genome-wide association study results for obesity in 4923 adults from northern Sweden.
[PMID 19526209] Is the thrifty genotype hypothesis supported by evidence based on confirmed type 2 diabetes- and obesity-susceptibility variants?
[PMID 19553259] Common body mass index-associated variants confer risk of extreme obesity.
[PMID 19910938] Novel obesity risk loci do not determine distribution of body fat depots: a whole-body MRI/MRS study.
[PMID 20127379] From monogenic to polygenic obesity: recent advances.
[PMID 20520848] Genetic markers of adult obesity risk are associated with greater early infancy weight gain and growth.
[PMID 20628085] First investigation of two obesity-related loci (TMEM18, FTO) concerning their association with educational level as well as income: the MONICA/KORA study.
[PMID 20712903] Obesity and diabetes genes are associated with being born small for gestational age: results from the Auckland Birthweight Collaborative study.
[PMID 20725061] MC4R variant is associated with BMI but not response to resistance training in young females.
[PMID 20824172] Physical activity attenuates the genetic predisposition to obesity in 20,000 men and women from EPIC-Norfolk prospective population study.
[PMID 21283731] FTO and MC4R gene variants are associated with obesity in polycystic ovary syndrome.
[PMID 21593506] Maternal and offspring adiposity-related genetic variants and gestational weight gain.
[PMID 21952719] Association of TMEM18 variants with BMI and waist circumference in children and correlation of mRNA expression in the PFC with body weight in rats.
[PMID 22179955] Genetic predictors of weight loss and weight regain after intensive lifestyle modification, metformin treatment, or standard care in the Diabetes Prevention Program.
[PMID 22466342] beta2-adrenergic receptor Thr164Ile polymorphism, obesity, and diabetes: comparison with FTO, MC4R, and TMEM18 polymorphisms in more than 64,000 individuals.
[PMID 23311614] Effects of smoking on the genetic risk of obesity: the population architecture using genomics and epidemiology study
[PMID 23775818] Elevated body mass index as a causal risk factor for symptomatic gallstone disease: a Mendelian randomization study.
[PMID 24762112] Increased body mass index, elevated C-reactive protein, and short telomere length
[PMID 27650258] A multianalytical approach to evaluate the association of 55 SNPs in 28 genes with obesity risk in North Indian adults.
[PMID 27829468] Fat mass obesity-associated (FTO) (rs9939609) and melanocortin 4 receptor (MC4R) (rs17782313) SNP are positively associated with obesity and blood pressure in Mexican school-aged children.
[PMID 30311592] Genetic risk score based on fat mass and obesity-associated, transmembrane protein 18 and fibronectin type III domain containing 5 polymorphisms is associated with anthropometric characteristics in South Brazilian children and adolescents.
[PMID 32109558] Implication of Genetic Variants in Overweight and Obesity susceptibility among the Young Arab Population of the United Arab Emirates.
[PMID 32228543] Obesity-related loci in TMEM18, CDKAL1 and FAIM2 are associated with obesity and type 2 diabetes in Chinese Han patients.
[PMID 32384785] Applicability of Obesity-Related SNPs and their Effect Size Measures Defined on Populations with European Ancestry for Genetic Risk Estimation among Roma.
