rs662(A;A)
From SNPedia
~2x higher risk of of coronary heart disease reported in some studies, but lower risk seen in other studies |
Is a | genotype |
of | rs662 |
Gene | PON1 |
Chromosome | 7 |
Position | 95,308,134 |
mentioned | by |
Magnitude | 2 |
Repute | Bad |
Geno | Mag | Summary |
---|---|---|
(A;A) | 2 | ~2x higher risk of of coronary heart disease reported in some studies, but lower risk seen in other studies |
(A;G) | 0.65x lower risk of ovarian cancer; higher risk of coronary heart disease in some studies; somewhat reduced PON catalytic efficiency | |
(G;G) | 1.3 | Mixed; conflicting results reported related to stroke and CAD |
see discussion at rs662