rs6696981
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Make rs6696981(G;G) |
| Make rs6696981(G;T) |
| Make rs6696981(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 1 |
| Position | 22376365 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs6696981 |
| dbSNP (classic) | rs6696981 |
| ClinGen | rs6696981 |
| ebi | rs6696981 |
| HLI | rs6696981 |
| Exac | rs6696981 |
| Gnomad | rs6696981 |
| Varsome | rs6696981 |
| LitVar | rs6696981 |
| Map | rs6696981 |
| PheGenI | rs6696981 |
| Biobank | rs6696981 |
| 1000 genomes | rs6696981 |
| hgdp | rs6696981 |
| ensembl | rs6696981 |
| geneview | rs6696981 |
| scholar | rs6696981 |
| rs6696981 | |
| pharmgkb | rs6696981 |
| gwascentral | rs6696981 |
| openSNP | rs6696981 |
| 23andMe | rs6696981 |
| SNPshot | rs6696981 |
| SNPdbe | rs6696981 |
| MSV3d | rs6696981 |
| GWAS Ctlg | rs6696981 |
| GMAF | 0.1809 |
| Max Magnitude | 0 |
| ? | (G;G) (G;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs6696981 increases susceptibility to Bone mineral density variations, lower for carriers of the G allele [PMID 18445777]
rs6696981 increases susceptibility to Osteoporotic fractures for carriers of the G allele [PMID 18445777]
| GWAS snp | |
|---|---|
| PMID | [PMID 19079262] |
| Trait | Bone mineral density (spine) |
| Title | New sequence variants associated with bone mineral density |
| Risk Allele | G |
| P-val | 2E-8 |
| Odds Ratio | 0.12 [0.08-0.16] SD decrease |
[PMID 22824048] Opposite associations of osteoprotegerin and ZBTB40 polymorphisms with bone mineral density of the hip in postmenopausal Taiwanese women
[PMID 19181680
] Common variants in the region around Osterix are associated with bone mineral density and growth in childhood.
[PMID 19629617] Replication study of candidate genes/loci associated with osteoporosis based on genome-wide screening.
[PMID 20554715] Analysis of recently identified osteoporosis susceptibility genes in Han Chinese women.
