rs6795970
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 0 | common in clinvar |
| Make rs6795970(A;G) |
| Make rs6795970(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 3 |
| Position | 38725184 |
| Gene | SCN10A |
| is a | snp |
| is | mentioned by |
| dbSNP | rs6795970 |
| dbSNP (classic) | rs6795970 |
| ClinGen | rs6795970 |
| ebi | rs6795970 |
| HLI | rs6795970 |
| Exac | rs6795970 |
| Gnomad | rs6795970 |
| Varsome | rs6795970 |
| LitVar | rs6795970 |
| Map | rs6795970 |
| PheGenI | rs6795970 |
| Biobank | rs6795970 |
| 1000 genomes | rs6795970 |
| hgdp | rs6795970 |
| ensembl | rs6795970 |
| geneview | rs6795970 |
| scholar | rs6795970 |
| rs6795970 | |
| pharmgkb | rs6795970 |
| gwascentral | rs6795970 |
| openSNP | rs6795970 |
| 23andMe | rs6795970 |
| SNPshot | rs6795970 |
| SNPdbe | rs6795970 |
| MSV3d | rs6795970 |
| GWAS Ctlg | rs6795970 |
| GMAF | 0.264 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
[PMID 20062061] Genetic variation in SCN10A influences cardiac conduction
| GWAS snp | |
|---|---|
| PMID | [PMID 20062063] |
| Trait | Electrocardiographic traits |
| Title | Several common variants modulate heart rate, PR interval and QRS duration |
| Risk Allele | A |
| P-val | 4E-9 |
| Odds Ratio | 5.17 [3.46-6.89] % SD increase |
[PMID 21041692
] Identification of genomic predictors of atrioventricular conduction: using electronic medical records as a tool for genome science
[PMID 20062060] Genome-wide association study of PR interval.
[PMID 21347284] Genome-wide association studies of the PR interval in African Americans.
| GWAS snp | |
|---|---|
| PMID | [PMID 23463857]
|
| Trait | Electrocardiographic conduction measures |
| Title | Genome- and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk. |
| Risk Allele | A |
| P-val | 5E-27 |
| Odds Ratio | .75 [NR] msec increase |
[PMID 24072447] Common SCN10A variants modulate PR interval and heart rate response during atrial fibrillation
[PMID 23092954] SHAVE: shrinkage estimator measured for multiple visits increases power in GWAS of quantitative traits.
[PMID 25085921] Common and Rare Variants in SCN10A Modulate the Risk of Atrial Fibrillation
[PMID 25691686] Common and Rare Variants in SCN10A Modulate the Risk of Atrial Fibrillation
[PMID 25691538] Role of common and rare variants in SCN10A: Results from the Brugada syndrome QRS locus gene discovery collaborative study
[PMID 26104176] Association Between Genetic Variation in the SCN10A Gene and Cardiac Conduction Abnormalities in Patients With Hypertrophic Cardiomyopathy
| ClinVar | |
|---|---|
| Risk | rs6795970(G;G) |
| Alt | rs6795970(G;G) |
| Reference | Rs6795970(A;A) |
| Significance | Non-pathogenic |
| Disease | not specified |
| Variation | info |
| Gene | SCN10A |
| CLNDBN | not specified |
| Reversed | 0 |
| HGVS | NC_000003.11:g.38766675A>G |
| CLNSRC | |
| CLNACC | RCV000249220.2, |
[PMID 30110000] [Rs17042171 at chromosome 4q25 is associated with atrial fibrillation in the Chinese Han population from the central plains].
[PMID 30538988] Homozygosity for the SCN10A Polymorphism rs6795970 Is Associated With Hypoalgesic Inflammatory Bowel Disease Phenotype.
