rs6797312
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 2x higher stroke risk in Caucasian women | |
| (A;T) | 2x higher stroke risk in Caucasian women | |
| (T;T) | normal |
| Reference | GRCh38 38.1/141 |
| Chromosome | 3 |
| Position | 167769515 |
| Gene | SERPINI1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs6797312 |
| dbSNP (classic) | rs6797312 |
| ClinGen | rs6797312 |
| ebi | rs6797312 |
| HLI | rs6797312 |
| Exac | rs6797312 |
| Gnomad | rs6797312 |
| Varsome | rs6797312 |
| LitVar | rs6797312 |
| Map | rs6797312 |
| PheGenI | rs6797312 |
| Biobank | rs6797312 |
| 1000 genomes | rs6797312 |
| hgdp | rs6797312 |
| ensembl | rs6797312 |
| geneview | rs6797312 |
| scholar | rs6797312 |
| rs6797312 | |
| pharmgkb | rs6797312 |
| gwascentral | rs6797312 |
| openSNP | rs6797312 |
| 23andMe | rs6797312 |
| SNPshot | rs6797312 |
| SNPdbe | rs6797312 |
| MSV3d | rs6797312 |
| GWAS Ctlg | rs6797312 |
| GMAF | 0.41 |
| Max Magnitude | 0 |
rs6797312, a SNP in the neuroserpin SERPINI1 gene, was found to be associated with stroke risk in some populations but not others.
In a study of 224 female patients (from 15-49 years old) equally divided between Caucasians and African-Americans, the rs6797312(A) allele was associated with higher risk (odds ratio 2.05, p=0.023) for early-onset ischemic stroke in Caucasians but showed no association in African-Americans.[PMID 17961231
]
