rs683395
From SNPedia
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 0 | |
| (C;C) | 1.3x risk | |
| (C;T) | 1.5x risk | |
| (T;T) | 0 | normal |
| Reference | GRCh38 38.1/141 |
| Chromosome | 3 |
| Position | 183152030 |
| Gene | LAMP3 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs683395 |
| dbSNP (classic) | rs683395 |
| ClinGen | rs683395 |
| ebi | rs683395 |
| HLI | rs683395 |
| Exac | rs683395 |
| Gnomad | rs683395 |
| Varsome | rs683395 |
| LitVar | rs683395 |
| Map | rs683395 |
| PheGenI | rs683395 |
| Biobank | rs683395 |
| 1000 genomes | rs683395 |
| hgdp | rs683395 |
| ensembl | rs683395 |
| geneview | rs683395 |
| scholar | rs683395 |
| rs683395 | |
| pharmgkb | rs683395 |
| gwascentral | rs683395 |
| openSNP | rs683395 |
| 23andMe | rs683395 |
| SNPshot | rs683395 |
| SNPdbe | rs683395 |
| MSV3d | rs683395 |
| GWAS Ctlg | rs683395 |
| GMAF | 0.1175 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs683395 has been reported in a large study to be associated with bipolar disorder.
The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with heterozygotes is 1.47 (CI 1.26-1.71), and for homozygotes, 1.3 (CI 0.69-2.46). [PMID 17554300
]
| GWAS | |
|---|---|
| SNP | rs683395 |
| PubMedID | [PMID 17554300]
|
| Condition | Bipolar disorder |
| Gene | NR |
| Risk Allele | G |
| pValue | 5.00E-006 |
| OR | 1.47 |
| 95% CI | 1.26-1.71 |
[PMID 19308021] Findings from bipolar disorder genome-wide association studies replicate in a Finnish bipolar family-cohort.
