rs684513
| Orientation | plus |
| Stabilized | plus |
| Make rs684513(C;C) |
| Make rs684513(C;G) |
| Make rs684513(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 15 |
| Position | 78566058 |
| Gene | CHRNA5 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs684513 |
| dbSNP (classic) | rs684513 |
| ClinGen | rs684513 |
| ebi | rs684513 |
| HLI | rs684513 |
| Exac | rs684513 |
| Gnomad | rs684513 |
| Varsome | rs684513 |
| LitVar | rs684513 |
| Map | rs684513 |
| PheGenI | rs684513 |
| Biobank | rs684513 |
| 1000 genomes | rs684513 |
| hgdp | rs684513 |
| ensembl | rs684513 |
| geneview | rs684513 |
| scholar | rs684513 |
| rs684513 | |
| pharmgkb | rs684513 |
| gwascentral | rs684513 |
| openSNP | rs684513 |
| 23andMe | rs684513 |
| SNPshot | rs684513 |
| SNPdbe | rs684513 |
| MSV3d | rs684513 |
| GWAS Ctlg | rs684513 |
| GMAF | 0.2456 |
| Max Magnitude | 0 |
| ? | (C;C) (C;G) (G;G) | 28 |
|---|---|---|
|
| ||
[PMID 20554942
] Nicotinic Acetylcholine Receptor Region on Chromosome 15q25 and Lung Cancer Risk Among African Americans: A Case-Control Study
[PMID 17135278] Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs.
[PMID 17373692] No evidence for association between 19 cholinergic genes and bipolar disorder.
[PMID 18163978] The CHRNA5/A3/B4 gene cluster variability as an important determinant of early alcohol and tobacco initiation in young adults.
[PMID 18165968] Identification of pharmacogenetic markers in smoking cessation therapy.
[PMID 18519524] Variants in nicotinic receptors and risk for nicotine dependence.
[PMID 18571741] Genetic variability in nicotinic acetylcholine receptors and nicotine addiction: converging evidence from human and animal research.
[PMID 19029397] Nicotinic receptor gene variants influence susceptibility to heavy smoking.
[PMID 19443489] Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5.
[PMID 20485328] Variation in nicotinic acetylcholine receptor genes is associated with multiple substance dependence phenotypes.
[PMID 20700436] Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.
[PMID 20886544] Risk gene variants for nicotine dependence in the CHRNA5-CHRNA3-CHRNB4 cluster are associated with cognitive performance.
[PMID 21430647] The galanin receptor 1 gene associates with tobacco craving in smokers seeking cessation treatment.
[PMID 26693074] CHRNA5 polymorphisms and risk of lung cancer in Chinese Han smokers.
