rs6993813
| Orientation | plus |
| Stabilized | plus |
| Make rs6993813(C;C) |
| Make rs6993813(C;T) |
| Make rs6993813(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 8 |
| Position | 119039999 |
| Gene | COLEC10 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs6993813 |
| dbSNP (classic) | rs6993813 |
| ClinGen | rs6993813 |
| ebi | rs6993813 |
| HLI | rs6993813 |
| Exac | rs6993813 |
| Gnomad | rs6993813 |
| Varsome | rs6993813 |
| LitVar | rs6993813 |
| Map | rs6993813 |
| PheGenI | rs6993813 |
| Biobank | rs6993813 |
| 1000 genomes | rs6993813 |
| hgdp | rs6993813 |
| ensembl | rs6993813 |
| geneview | rs6993813 |
| scholar | rs6993813 |
| rs6993813 | |
| pharmgkb | rs6993813 |
| gwascentral | rs6993813 |
| openSNP | rs6993813 |
| 23andMe | rs6993813 |
| SNPshot | rs6993813 |
| SNPdbe | rs6993813 |
| MSV3d | rs6993813 |
| GWAS Ctlg | rs6993813 |
| GMAF | 0.3788 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs6993813 increases susceptibility to Bone mineral density variations, lower for carriers of the A allele [PMID 18445777]
rs6993813 increases susceptibility to Osteoporotic fractures for carriers of the A allele [PMID 18445777]
| GWAS | |
|---|---|
| SNP | rs6993813 |
| PubMedID | [PMID 18445777] |
| Condition | Bone mineral density (hip) |
| Gene | OPG |
| Risk Allele | C |
| pValue | 3.00E-011 |
| OR | 0.09 |
| 95% CI | 0.07-0.12) SD decreas |
[PMID 22079369] TNFRSF11B gene haplotype and its association with bone mineral density variations in postmenopausal Mexican-Mestizo women
[PMID 22824048] Opposite associations of osteoprotegerin and ZBTB40 polymorphisms with bone mineral density of the hip in postmenopausal Taiwanese women
[PMID 19181680
] Common variants in the region around Osterix are associated with bone mineral density and growth in childhood.
[PMID 20534768] OPG and RANK polymorphisms are both associated with cortical bone mineral density: findings from a metaanalysis of the Avon longitudinal study of parents and children and gothenburg osteoporosis and obesity determinants cohorts.
[PMID 20554715] Analysis of recently identified osteoporosis susceptibility genes in Han Chinese women.
[PMID 24130145] Polymorphism of LRP5, but not of TNFRSF11B, is associated with a decrease in bone mineral density in postmenopausal maya-mestizo women
[PMID 23531404] Association of genetic polymorphisms of RANK, RANKL and OPG with bone mineral density in Chinese peri- and postmenopausal women.
[PMID 25105978] An Osteoprotegerin Gene Polymorphism Is Associated with an Increased Risk of Hip Fracture in Japanese Patients with Rheumatoid Arthritis: Results from the IORRA Observational Cohort Study
