rs7014346
| Orientation | plus |
| Stabilized | plus |
| Make rs7014346(A;A) |
| Make rs7014346(A;G) |
| Make rs7014346(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 8 |
| Position | 127412547 |
| Gene | CASC8 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs7014346 |
| dbSNP (classic) | rs7014346 |
| ClinGen | rs7014346 |
| ebi | rs7014346 |
| HLI | rs7014346 |
| Exac | rs7014346 |
| Gnomad | rs7014346 |
| Varsome | rs7014346 |
| LitVar | rs7014346 |
| Map | rs7014346 |
| PheGenI | rs7014346 |
| Biobank | rs7014346 |
| 1000 genomes | rs7014346 |
| hgdp | rs7014346 |
| ensembl | rs7014346 |
| geneview | rs7014346 |
| scholar | rs7014346 |
| rs7014346 | |
| pharmgkb | rs7014346 |
| gwascentral | rs7014346 |
| openSNP | rs7014346 |
| 23andMe | rs7014346 |
| SNPshot | rs7014346 |
| SNPdbe | rs7014346 |
| MSV3d | rs7014346 |
| GWAS Ctlg | rs7014346 |
| GMAF | 0.326 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
[PMID 18839428] colorectal cancer rs10505477 and rs6983267 yielded allelic p-values of 1.42 x 10(-7) and 2.57 x 10(-7), respectively with OR=1.50 (95% CI: 1.29-1.75). Risk region was delineated by SNPs rs10505477 and rs7014346 and comprised 17 kb
| GWAS | |
|---|---|
| SNP | rs7014346 |
| PubMedID | [PMID 18372901 ]
|
| Condition | Colorectal cancer |
| Gene | POU5FIP1, HsG57825, DQ515897 |
| Risk Allele | A |
| pValue | 9.00E-026 |
| OR | 1.19 |
| 95% CI | 1.15-1.23 |
[PMID 20659471] Genetic Heterogeneity in Colorectal Cancer Associations in Americans of African vs. European Descent
[PMID 21097774] Colorectal cancer susceptibility loci on chromosome 8q23.3 and 11q23.1 as modifiers for disease expression in lynch syndrome
[PMID 19011631] Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer.
[PMID 19857256] Association between an 8q24 locus and the risk of colorectal cancer in Japanese.
[PMID 23359760] Single-nucleotide polymorphism associations for colorectal cancer in southern chinese population
[PMID 22848671] Association of eleven common, low-penetrance colorectal cancer susceptibility genetic variants at six risk loci with clinical outcome.
[PMID 26579801] Correlation Between CASC8, SMAD7 Polymorphisms and the Susceptibility to Colorectal Cancer: An Updated Meta-Analysis Based on GWAS Results
[PMID 26885031] Association of 8q23-24 region (8q23.3 loci and 8q24.21 loci) with susceptibility to colorectal cancer: a systematic and updated meta-analysis.
[PMID 27689194] Single Nucleotide Polymorphisms within the 8Q24 Region are Not Associated with the Risk of Intraductal Papillary Mucinous Neoplasms of the Pancreas.
[PMID 27769063] Risk of eighteen genome-wide association study-identified genetic variants for colorectal cancer and colorectal adenoma in Han Chinese.
