rs710446

Orientation

minus

Stabilized

minus

Make rs710446(A;A)

Make rs710446(A;G)

Make rs710446(G;G)

Reference

GRCh38 38.1/141

Chromosome

3

Position

186742138

Gene

KNG1

is a	snp
is	mentioned by
dbSNP	rs710446
dbSNP (classic)	rs710446
ClinGen	rs710446
ebi	rs710446
HLI	rs710446
Exac	rs710446
Gnomad	rs710446
Varsome	rs710446
LitVar	rs710446
Map	rs710446
PheGenI	rs710446
Biobank	rs710446
1000 genomes	rs710446
hgdp	rs710446
ensembl	rs710446
geneview	rs710446
scholar	rs710446
google	rs710446
pharmgkb	rs710446
gwascentral	rs710446
openSNP	rs710446
23andMe	rs710446
SNPshot	rs710446
SNPdbe	rs710446
MSV3d	rs710446
GWAS Ctlg	rs710446

GMAF

0.4192

Max Magnitude

0

?

(A;A) (A;G) (G;G)

28

GWAS snp
PMID	[PMID 20303064 ]
Trait	Activated partial thromboplastin time
Title	Common Variants of Large Effect in F12, KNG1, and HRG Are Associated with Activated Partial Thromboplastin Time
Risk Allele	G
P-val	1E-21
Odds Ratio	0.36 [0.29-0.43] unit decrease

[PMID 21270443] KNG1 Ile581Thr and susceptibility to venous thrombosis.

GWAS snp
PMID	[PMID 22703881 ]
Trait
Title	Genetic Associations for Activated Partial Thromboplastin Time and Prothrombin Time, their Gene Expression Profiles, and Risk of Coronary Artery Disease.
Risk Allele	C
P-val	0
Odds Ratio	1.1800 None

[PMID 22701019] A genome-wide association study identifies KNG1 as a genetic determinant of plasma factor XI Level and activated partial thromboplastin time.

[PMID 25779970 ] Gene-centric approach identifies new and known loci for FVIII activity and VWF antigen levels in European Americans and African Americans

[PMID 26159646] Variants in the Atherogenic ALOX5AP, THBD, and KNG1 Genes Potentiate the Risk of Ischemic Stroke via a Genetic Main Effect and Epistatic Interactions in a Chinese Population

[PMID 30478260 ] Genetic effects of BDKRB2 and KNG1 on deep venous thrombosis after orthopedic surgery and the potential mediator.