rs7105934

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(A;A)	2.1	0.48 times lower odds of developing renal cell carcinoma
(A;G)	2	0.69 times lower odds of developing renal cell carcinoma
(G;G)	0	common in complete genomics

Reference

GRCh38 38.1/141

Chromosome

11

Position

69424973

Gene	LOC102724265

is a	snp
is	mentioned by
dbSNP	rs7105934
dbSNP (classic)	rs7105934
ClinGen	rs7105934
ebi	rs7105934
HLI	rs7105934
Exac	rs7105934
Gnomad	rs7105934
Varsome	rs7105934
LitVar	rs7105934
Map	rs7105934
PheGenI	rs7105934
Biobank	rs7105934
1000 genomes	rs7105934
hgdp	rs7105934
ensembl	rs7105934
geneview	rs7105934
scholar	rs7105934
google	rs7105934
pharmgkb	rs7105934
gwascentral	rs7105934
openSNP	rs7105934
23andMe	rs7105934
SNPshot	rs7105934
SNPdbe	rs7105934
MSV3d	rs7105934
GWAS Ctlg	rs7105934

GMAF

0.2052

Max Magnitude

2.1

?	(A;A) (A;G) (G;G)	28

GWAS snp
PMID	[PMID 21131975]
Trait
Title	Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3
Risk Allele
P-val	8E-14
Odds Ratio	1.4500 [1.32-1.61]

23andMe reports that each A allele at rs7105934 is associated with 0.69 times lower odds of developing renal cell carcinoma (a form of kidney cancer). [PMID 21131975]

[PMID 22131124] Chromosome 11q13.3 variant modifies renal cell cancer risk in a Chinese population

[PMID 23911636] Germline genetic variations at 11q13 and 12p11 locus modulate age of onset for renal cell carcinoma

[PMID 24220910] A genome-wide association study of renal cell carcinoma among African Americans