rs712

Orientation

minus

Stabilized

minus

Geno	Mag	Summary
(T;T)	0	common in clinvar

Make rs712(G;G)

Make rs712(G;T)

Reference

GRCh38 38.1/141

Chromosome

12

Position

25209618

Gene

KRAS

is a	snp
is	mentioned by
dbSNP	rs712
dbSNP (classic)	rs712
ClinGen	rs712
ebi	rs712
HLI	rs712
Exac	rs712
Gnomad	rs712
Varsome	rs712
LitVar	rs712
Map	rs712
PheGenI	rs712
Biobank	rs712
1000 genomes	rs712
hgdp	rs712
ensembl	rs712
geneview	rs712
scholar	rs712
google	rs712
pharmgkb	rs712
gwascentral	rs712
openSNP	rs712
23andMe	rs712
SNPshot	rs712
SNPdbe	rs712
MSV3d	rs712
GWAS Ctlg	rs712

GMAF

0.4725

Max Magnitude

0

?	(G;G) (G;T) (T;T)	28

[PMID 21688344] Effects of KRAS mutation and polymorphism on the risk and prognosis of oral squamous cell carcinoma

[PMID 24552817] Extensive sequence variation in the 3' untranslated region of the KRAS gene in lung and ovarian cancer cases

[PMID 23729275] A let-7 binding site polymorphism rs712 in the KRAS 3' UTR is associated with an increased risk of gastric cancer.

[PMID 26515332] KRAS polymorphisms are associated with survival of CRC in Chinese population

[PMID 26535719] An let-7 KRAS rs712 polymorphism increases hepatocellular carcinoma risk

[PMID 26543374] rs712 polymorphism within let-7 microRNA-binding site might be involved in the initiation and progression of colorectal cancer in Chinese population

ClinVar
Risk	rs712(G;G)
Alt	rs712(G;G)
Reference	Rs712(T;T)
Significance	Probable-non-pathogenic
Disease	Cardio-facio-cutaneous syndrome Noonan syndrome
Variation	info
Gene	KRAS
CLNDBN	Cardio-facio-cutaneous syndrome Noonan syndrome
Reversed	1
HGVS	NC_000012.11:g.25362552A>C
CLNSRC
CLNACC	RCV000332687.1, RCV000382642.1,

[PMID 33390813] Association analysis between the interaction of RAS family genes mutations and papillary thyroid carcinoma in the Han Chinese population.