rs7120118
| Orientation | plus |
| Stabilized | plus |
| Make rs7120118(C;C) |
| Make rs7120118(C;T) |
| Make rs7120118(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 11 |
| Position | 47264739 |
| Gene | NR1H3 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs7120118 |
| dbSNP (classic) | rs7120118 |
| ClinGen | rs7120118 |
| ebi | rs7120118 |
| HLI | rs7120118 |
| Exac | rs7120118 |
| Gnomad | rs7120118 |
| Varsome | rs7120118 |
| LitVar | rs7120118 |
| Map | rs7120118 |
| PheGenI | rs7120118 |
| Biobank | rs7120118 |
| 1000 genomes | rs7120118 |
| hgdp | rs7120118 |
| ensembl | rs7120118 |
| geneview | rs7120118 |
| scholar | rs7120118 |
| rs7120118 | |
| pharmgkb | rs7120118 |
| gwascentral | rs7120118 |
| openSNP | rs7120118 |
| 23andMe | rs7120118 |
| SNPshot | rs7120118 |
| SNPdbe | rs7120118 |
| MSV3d | rs7120118 |
| GWAS Ctlg | rs7120118 |
| GMAF | 0.4637 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
| GWAS snp | |
|---|---|
| PMID | [PMID 19060910 ]
|
| Trait | HDL cholesterol |
| Title | Genome-wide association analysis of metabolic traits in a birth cohort from a founder population |
| Risk Allele | G |
| P-val | 4E-8 |
| Odds Ratio | 0.04 [0.03-0.05] mmol/l increase |
The C allele of this SNP in the NR1H3 gene is associated with increased (but still low) risk of progressive supranuclear palsy. [PMID 17357082]
[PMID 22029530] A common polymorphism in NR1H2 (LXRbeta) is associated with preeclampsia
[PMID 22027013] Genetic analysis of genes involved in amyloid-β degradation and clearance in Alzheimer's disease
[PMID 19299407] Replication of genetic associations with plasma lipoprotein traits in a multiethnic sample.
[PMID 21562465] Liver X receptor alpha gene polymorphisms and variable cardiovascular outcomes in patients treated with antihypertensive therapy: results from the INVEST-GENES study.
[PMID 23838803] Association of liver X receptors (LXRs) genetic variants to gallbladder cancer susceptibility
[PMID 27070640] MADD-FOLH1 Polymorphisms and Their Haplotypes with Serum Lipid Levels and the Risk of Coronary Heart Disease and Ischemic Stroke in a Chinese Han Population
[PMID 28244008] Liver X Receptor Genes Variants Modulate ALS Phenotype.
