rs72558189
From SNPedia
| Warfarin (Coumadin®) |
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 2.5 | CYP2C9*14 homozygote |
| (A;G) | carrier of one CYP2C9*14 allele | |
| (G;G) | 0 | normal |
| Reference | GRCh38 38.1/141 |
| Chromosome | 10 |
| Position | 94942234 |
| Gene | CYP2C9 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs72558189 |
| dbSNP (classic) | rs72558189 |
| ClinGen | rs72558189 |
| ebi | rs72558189 |
| HLI | rs72558189 |
| Exac | rs72558189 |
| Gnomad | rs72558189 |
| Varsome | rs72558189 |
| LitVar | rs72558189 |
| Map | rs72558189 |
| PheGenI | rs72558189 |
| Biobank | rs72558189 |
| 1000 genomes | rs72558189 |
| hgdp | rs72558189 |
| ensembl | rs72558189 |
| geneview | rs72558189 |
| scholar | rs72558189 |
| rs72558189 | |
| pharmgkb | rs72558189 |
| gwascentral | rs72558189 |
| openSNP | rs72558189 |
| 23andMe | rs72558189 |
| SNPshot | rs72558189 |
| SNPdbe | rs72558189 |
| MSV3d | rs72558189 |
| GWAS Ctlg | rs72558189 |
| Max Magnitude | 2.5 |
| This SNP has been recognized by the Coriell Personalized Medicine Collaborative ICOB.
|
rs72558189, also known as 374G>A, 3552G>A or R125H, is a SNP in the CYP2C9 gene.
The rs72558189(A) allele defines the CYP2C9*14 variant, which may have decreased activity.
| ClinVar | |
|---|---|
| Risk | Rs72558189(A;A) |
| Alt | Rs72558189(A;A) |
| Reference | Rs72558189(G;G) |
| Significance | Untested |
| Disease | |
| Variation | info |
| Gene | CYP2C9 |
| CLNDBN | |
| Reversed | 0 |
| HGVS | NC_000010.10:g.96701991G>A |
| CLNSRC | |
| CLNACC | |
[PMID 15371982] Novel CYP2C9 genetic variants in Asian subjects and their influence on maintenance warfarin dose.
[PMID 16099926] Functional characterization of novel allelic variants of CYP2C9 recently discovered in southeast Asians.
