rs72973581
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 2.5 | Somewhat (0.4x?) lower risk for Alzheimer's, according to one study |
| (A;G) | 2 | Slightly lower risk (0.57x) for Alzheimer's, according to one study |
| (G;G) | 0 | common/normal |
| Reference | GRCh38.p7 38.3/150 |
| Chromosome | 19 |
| Position | 1043104 |
| Gene | ABCA7 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs72973581 |
| dbSNP (classic) | rs72973581 |
| ClinGen | rs72973581 |
| ebi | rs72973581 |
| HLI | rs72973581 |
| Exac | rs72973581 |
| Gnomad | rs72973581 |
| Varsome | rs72973581 |
| LitVar | rs72973581 |
| Map | rs72973581 |
| PheGenI | rs72973581 |
| Biobank | rs72973581 |
| 1000 genomes | rs72973581 |
| hgdp | rs72973581 |
| ensembl | rs72973581 |
| geneview | rs72973581 |
| scholar | rs72973581 |
| rs72973581 | |
| pharmgkb | rs72973581 |
| gwascentral | rs72973581 |
| openSNP | rs72973581 |
| 23andMe | rs72973581 |
| SNPshot | rs72973581 |
| SNPdbe | rs72973581 |
| MSV3d | rs72973581 |
| GWAS Ctlg | rs72973581 |
| Max Magnitude | 2.5 |
A sequencing study of 332 sporadic Alzheimer's disease cases identified this ABCA7 coding variant, rs72973581(A), also known as p.G215S, as conferring a modest but statistically significant protection against the disorder (OR 0.57, CI: 0.41-0.8, p = 0.024).[PMID 27289440
]
