rs7310409
| Orientation | plus |
| Stabilized | plus |
| Make rs7310409(A;A) |
| Make rs7310409(A;G) |
| Make rs7310409(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 12 |
| Position | 120987058 |
| Gene | HNF1A |
| is a | snp |
| is | mentioned by |
| dbSNP | rs7310409 |
| dbSNP (classic) | rs7310409 |
| ClinGen | rs7310409 |
| ebi | rs7310409 |
| HLI | rs7310409 |
| Exac | rs7310409 |
| Gnomad | rs7310409 |
| Varsome | rs7310409 |
| LitVar | rs7310409 |
| Map | rs7310409 |
| PheGenI | rs7310409 |
| Biobank | rs7310409 |
| 1000 genomes | rs7310409 |
| hgdp | rs7310409 |
| ensembl | rs7310409 |
| geneview | rs7310409 |
| scholar | rs7310409 |
| rs7310409 | |
| pharmgkb | rs7310409 |
| gwascentral | rs7310409 |
| openSNP | rs7310409 |
| 23andMe | rs7310409 |
| SNPshot | rs7310409 |
| SNPdbe | rs7310409 |
| MSV3d | rs7310409 |
| GWAS Ctlg | rs7310409 |
| GMAF | 0.3935 |
| Max Magnitude | 0 |
A study of 12,854 Japanese subjects replicated the finding of an association between rs7310409 and serum CRP levels.[PMID 21196492]
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
| GWAS | |
|---|---|
| SNP | rs7310409 |
| PubMedID | [PMID 18439548 ]
|
| Condition | C-reactive protein |
| Gene | HNF1A |
| Risk Allele | A |
| pValue | 7.00E-017 |
| OR | 0.15 |
| 95% CI | NR) mg/dl decreas |
| GWAS snp | |
|---|---|
| PMID | [PMID 21196492] |
| Trait | |
| Title | Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus |
| Risk Allele | G |
| P-val | 3E-8 |
| Odds Ratio | 0.0700 [0.04-0.10] unit increase |
| GWAS snp | |
|---|---|
| PMID | [PMID 22001757]
|
| Trait | |
| Title | Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. |
| Risk Allele | G |
| P-val | 7E-45 |
| Odds Ratio | 6.8000 None |
[PMID 18439552] Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein.
[PMID 18852197] Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants.
[PMID 19197348] Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.
[PMID 19474294] Potential etiologic and functional implications of genome-wide association loci for human diseases and traits.
[PMID 20031577] Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study.
[PMID 21195701] Effect of obesity on the association between common variations in the HNF1A gene region and C-reactive protein level in Taiwanese.
[PMID 21498636] Genome-wide "pleiotropy scan" identifies HNF1A region as a novel pancreatic cancer susceptibility locus.
[PMID 21647738] Genome-wide association with C-reactive protein levels in CLHNS: evidence for the CRP and HNF1A loci and their interaction with exposure to a pathogenic environment.
[PMID 22569176] MALDI-TOF mass spectrometry screening of cholelithiasis risk markers in the gene of HNF1alpha.
[PMID 23092954] SHAVE: shrinkage estimator measured for multiple visits increases power in GWAS of quantitative traits.
[PMID 23183503] Variants within HNF1alpha and ANGPTL4 genes and acute coronary syndrome in Czech population. The GENDEMIP study.
[PMID 24671014] Genetic risk assessment for cardiovascular disease with seven genes associated with plasma C-reactive protein concentrations in Asian populations
