rs7579899
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Make rs7579899(A;A) |
| Make rs7579899(A;G) |
| Make rs7579899(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 2 |
| Position | 46310465 |
| Gene | EPAS1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs7579899 |
| dbSNP (classic) | rs7579899 |
| ClinGen | rs7579899 |
| ebi | rs7579899 |
| HLI | rs7579899 |
| Exac | rs7579899 |
| Gnomad | rs7579899 |
| Varsome | rs7579899 |
| LitVar | rs7579899 |
| Map | rs7579899 |
| PheGenI | rs7579899 |
| Biobank | rs7579899 |
| 1000 genomes | rs7579899 |
| hgdp | rs7579899 |
| ensembl | rs7579899 |
| geneview | rs7579899 |
| scholar | rs7579899 |
| rs7579899 | |
| pharmgkb | rs7579899 |
| gwascentral | rs7579899 |
| openSNP | rs7579899 |
| 23andMe | rs7579899 |
| SNPshot | rs7579899 |
| SNPdbe | rs7579899 |
| MSV3d | rs7579899 |
| GWAS Ctlg | rs7579899 |
| GMAF | 0.4389 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
| GWAS snp | |
|---|---|
| PMID | [PMID 21131975 ]
|
| Trait | |
| Title | Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3 |
| Risk Allele | |
| P-val | 2E-9 |
| Odds Ratio | 1.1500 [1.10-1.21] |
23andMe reports that rs7579899(A,A) homozygotes are 1.15 times more likely, and (G,G) homozygotes 1.15 times less likely, than (A,G) heterozygotes to develop renal cell carcinoma (a form of kidney cancer). [PMID 21131975]
[PMID 22131124] Chromosome 11q13.3 variant modifies renal cell cancer risk in a Chinese population
[PMID 22113997] The chromosome 2p21 region harbors a complex genetic architecture for association with risk for renal cell carcinoma
