rs76546355
From SNPedia
| (A) allele has increased risk of Behçet's disease |
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 5.46 | increased risk of Behçet's disease |
| (A;G) | 5.46 | increased risk of Behçet's disease |
| (G;G) | 0 | common in complete genomics |
| Reference | GRCh38 38.1/141 |
| Chromosome | 6 |
| Position | 31381371 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs76546355 |
| dbSNP (classic) | rs76546355 |
| ClinGen | rs76546355 |
| ebi | rs76546355 |
| HLI | rs76546355 |
| Exac | rs76546355 |
| Gnomad | rs76546355 |
| Varsome | rs76546355 |
| LitVar | rs76546355 |
| Map | rs76546355 |
| PheGenI | rs76546355 |
| Biobank | rs76546355 |
| 1000 genomes | rs76546355 |
| hgdp | rs76546355 |
| ensembl | rs76546355 |
| geneview | rs76546355 |
| scholar | rs76546355 |
| rs76546355 | |
| pharmgkb | rs76546355 |
| gwascentral | rs76546355 |
| openSNP | rs76546355 |
| 23andMe | rs76546355 |
| SNPshot | rs76546355 |
| SNPdbe | rs76546355 |
| MSV3d | rs76546355 |
| GWAS Ctlg | rs76546355 |
| Merged from | Rs116799036 |
| Max Magnitude | 5.46 |
rs76546355 (A) is a risk allele for Behçet's disease.
HLA-B*51 allele and the rs76546355 MHC SNP are independent genetic risk factors for Behçet's disease in Iranian, and that positivity for the rs76546355 risk allele, but not for B*51, does correlate with specific demographic characteristics or clinical manifestations in Behçet's disease patients
[PMID 25889189
] Characterization of the major histocompatibility complex locus association with Behçet's disease in Iran
