GWAS snp
|
PMID
|
[PMID 18439548]
|
Trait
|
C-reactive protein
|
Title
|
Loci Related to Metabolic-Syndrome Pathways Including LEPR, HNF1A, IL6R, and GCKR Associate with Plasma C-Reactive Protein: The Women's Genome Health Study
|
Risk Allele
|
|
P-val
|
8.9999999999999994E-21
|
Odds Ratio
|
0.26 [NR] mg/dl decrease
|
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[PMID 19802338] Genetic loci associated with plasma concentration of low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, apolipoprotein A1, and Apolipoprotein B among 6382 white women in genome-wide analysis with replication.
[PMID 20031577] Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study.
[PMID 21647738] Genome-wide association with C-reactive protein levels in CLHNS: evidence for the CRP and HNF1A loci and their interaction with exposure to a pathogenic environment.
[PMID 22234866] Evidence from case-control and longitudinal studies supports associations of genetic variation in APOE, CETP, and IL6 with human longevity.
[PMID 24468470] Genetic susceptibility to accelerated cognitive decline in the US Health and Retirement Study
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