2x increased risk for Type-2 diabetes |
Geno
|
Mag
|
Summary
|
(C;C)
|
2
|
Normal (lower) risk of Type 2 Diabetes and Gestational Diabetes.
|
(C;T)
|
2.1
|
1.4x increased risk for diabetes (and perhaps colon cancer).
|
(T;T)
|
3.5
|
2x increased risk for Type-2 diabetes
|
This genotype doubles the risk of Type-2 diabetes, [PMID 17671651] and also Gestational Diabetes. Also increased risk of colo-rectal cancer. Reduced insulin secretion in the pancreas. This has been confirmed in most races. In African Americans it even affects young people.