rs7927894
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 2 | 0.83x lower risk of Atopic Dermatitis. |
| (C;T) | 1.9 | Normal risk of Atopic Dermatitis. |
| (T;T) | 2 | 1.2x higher risk of Atopic Dermatitis. |
| Reference | GRCh38 38.1/141 |
| Chromosome | 11 |
| Position | 76590272 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs7927894 |
| dbSNP (classic) | rs7927894 |
| ClinGen | rs7927894 |
| ebi | rs7927894 |
| HLI | rs7927894 |
| Exac | rs7927894 |
| Gnomad | rs7927894 |
| Varsome | rs7927894 |
| LitVar | rs7927894 |
| Map | rs7927894 |
| PheGenI | rs7927894 |
| Biobank | rs7927894 |
| 1000 genomes | rs7927894 |
| hgdp | rs7927894 |
| ensembl | rs7927894 |
| geneview | rs7927894 |
| scholar | rs7927894 |
| rs7927894 | |
| pharmgkb | rs7927894 |
| gwascentral | rs7927894 |
| openSNP | rs7927894 |
| 23andMe | rs7927894 |
| SNPshot | rs7927894 |
| SNPdbe | rs7927894 |
| MSV3d | rs7927894 |
| GWAS Ctlg | rs7927894 |
| GMAF | 0.2819 |
| Max Magnitude | 2 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
23andMe blog associated rs7927894(T) with Crohn’s disease 1.16x and atopic dermatitis
| GWAS snp | |
|---|---|
| PMID | [PMID 19349984] |
| Trait | Atopic dermatitis |
| Title | A common variant on chromosome 11q13 is associated with atopic dermatitis |
| Risk Allele | A |
| P-val | 8E-10 |
| Odds Ratio | |
| GWAS snp | |
|---|---|
| PMID | [PMID 18587394 ]
|
| Trait | Crohn's disease |
| Title | Genome-wide assocation defines more than 30 distinct susceptibility loci for Crohn's disease |
| Risk Allele | T |
| P-val | 1.0000000000000001E-9 |
| Odds Ratio | 1.16 [NR] |
[PMID 20109745] Chromosome 11q13.5 variant associated with childhood eczema: An effect supplementary to filaggrin mutations
[PMID 20706116] Genome-wide approaches to the etiology of eczema
[PMID 21752155] Genetic susceptibility to inflammation and colonic transit in lower functional gastrointestinal disorders: preliminary analysis
[PMID 22197932] Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis
[PMID 19068216] Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship.
[PMID 21304977] An investigation of genome-wide studies reported susceptibility loci for ulcerative colitis shows limited replication in north Indians.
[PMID 21429916] The eczema risk variant on chromosome 11q13 (rs7927894) in the population-based ALSPAC cohort: a novel susceptibility factor for asthma and hay fever.
[PMID 23557745] Association of the chromosome 11q13.5 variant with atopic dermatitis in Austrian patients
