rs798766

plus

Geno	Mag	Summary
(T;T)	1	Increased susceptibility urinary bladder cancer

Make rs798766(C;C)

Make rs798766(C;T)

Reference

GRCh38 38.1/141

Chromosome

4

Position

1732512

Gene

TACC3

is a	snp
is	mentioned by
dbSNP	rs798766
dbSNP (classic)	rs798766
ClinGen	rs798766
ebi	rs798766
HLI	rs798766
Exac	rs798766
Gnomad	rs798766
Varsome	rs798766
LitVar	rs798766
Map	rs798766
PheGenI	rs798766
Biobank	rs798766
1000 genomes	rs798766
hgdp	rs798766
ensembl	rs798766
geneview	rs798766
scholar	rs798766
google	rs798766
pharmgkb	rs798766
gwascentral	rs798766
openSNP	rs798766
23andMe	rs798766
SNPshot	rs798766
SNPdbe	rs798766
MSV3d	rs798766
GWAS Ctlg	rs798766

GMAF

0.2236

Max Magnitude

1

?

(C;C) (C;T) (T;T)

28

GWAS snp
PMID	[PMID 20348956 ]
Trait	Urinary bladder cancer
Title	A sequence variant at 4p16.3 confers susceptibility to urinary bladder cancer
Risk Allele	T
P-val	1E-11
Odds Ratio	1.24 [1.17-1.32]

The T allele at rs798766 is associated with 1.24 higher odds of bladder cancer. [PMID 20348956 ]

GWAS snp
PMID	[PMID 20972438 ]
Trait
Title	A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci
Risk Allele	T
P-val	4E-13
Odds Ratio	1.2000 [1.14-1.26]

OMIM	109800
Desc
Variant
Related	also

[PMID 21459758 ] Chromosome 4p16.3 variant modify bladder cancer risk in a Chinese population.

[PMID 23053209] Genetic polymorphisms on 8q24.1 and 4p16.3 are not linked with urothelial carcinoma of the bladder in contrast to their association with aggressive upper urinary tract tumours

[PMID 22711262] Systematic evaluation of bladder cancer risk-associated single-nucleotide polymorphisms in a Chinese population.

GWAS snp
PMID	[PMID 24163127 ]
Trait	Bladder cancer
Title	Genome-wide association study identifies multiple loci associated with bladder cancer risk.
Risk Allele	T
P-val	7E-25
Odds Ratio	1.22 [1.18-1.27]

[PMID 32384449 ] Genetic risk scores based on risk-associated single nucleotide polymorphisms can reveal inherited risk of bladder cancer in Chinese population.