rs80357605

minus

Geno	Mag	Summary
(-;TCAA)	6	BRCA1 variant considered pathogenic for breast cancer
(TCAA;TCAA)	0	common in clinvar

Make rs80357605(-;-)

Reference

GRCh38 38.1/141

Chromosome

17

Position

43092801

Gene

BRCA1

is a	snp
is	mentioned by
dbSNP	rs80357605
dbSNP (classic)	rs80357605
ClinGen	rs80357605
ebi	rs80357605
HLI	rs80357605
Exac	rs80357605
Gnomad	rs80357605
Varsome	rs80357605
LitVar	rs80357605
Map	rs80357605
PheGenI	rs80357605
Biobank	rs80357605
1000 genomes	rs80357605
hgdp	rs80357605
ensembl	rs80357605
geneview	rs80357605
scholar	rs80357605
google	rs80357605
pharmgkb	rs80357605
gwascentral	rs80357605
openSNP	rs80357605
23andMe	rs80357605
SNPshot	rs80357605
SNPdbe	rs80357605
MSV3d	rs80357605
GWAS Ctlg	rs80357605

Merged from

Rs80357917

Max Magnitude

6

rs80357605, also known as 2846del4, c.2727_2730delTCAA and p.Asn909_Gln910?fs, is a variant in the BRCA1 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80357605(AATC;AATC) rs80357605(-;-)
Alt	rs80357605(AATC;AATC) rs80357605(-;-)
Reference	Rs80357605(TCAA;TCAA)
Significance	Pathogenic
Disease	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer Hereditary cancer-predisposing syndrome
Variation	info
Gene	BRCA1
CLNDBN	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer, familial 1 Hereditary cancer-predisposing syndrome
Reversed	1
HGVS	NC_000017.10:g.41244818_41244821delTTGA
CLNSRC	Breast Cancer Information Core (BRCA1)
CLNACC	RCV000047948.4, RCV000083188.8, RCV000162859.1,