rs80357635

minus

Geno	Mag	Summary
(-;AG)	6	BRCA1 variant considered pathogenic for breast cancer
(AG;AG)	0	Normal

Make rs80357635(-;-)

Reference

GRCh38 38.1/141

Chromosome

17

Position

43092302

Gene

BRCA1

is a	snp
is	mentioned by
dbSNP	rs80357635
dbSNP (classic)	rs80357635
ClinGen	rs80357635
ebi	rs80357635
HLI	rs80357635
Exac	rs80357635
Gnomad	rs80357635
Varsome	rs80357635
LitVar	rs80357635
Map	rs80357635
PheGenI	rs80357635
Biobank	rs80357635
1000 genomes	rs80357635
hgdp	rs80357635
ensembl	rs80357635
geneview	rs80357635
scholar	rs80357635
google	rs80357635
pharmgkb	rs80357635
gwascentral	rs80357635
openSNP	rs80357635
23andMe	rs80357635
SNPshot	rs80357635
SNPdbe	rs80357635
MSV3d	rs80357635
GWAS Ctlg	rs80357635

Max Magnitude

6

rs80357635, also known as 3347delAG, c.3228_3229delAG and p.Arg1076_Gly1077ArgAlafs, is a variant in the BRCA1 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80357635(-;-)
Alt	rs80357635(-;-)
Reference	Rs80357635(AG;AG)
Significance	Pathogenic
Disease	Breast-ovarian cancer not provided Hereditary cancer-predisposing syndrome Hereditary breast and ovarian cancer syndrome Familial cancer of breast
Variation	info
Gene	BRCA1
CLNDBN	Breast-ovarian cancer, familial 1 not provided Hereditary cancer-predisposing syndrome Hereditary breast and ovarian cancer syndrome Familial cancer of breast
Reversed	1
HGVS	NC_000017.10:g.41244319_41244320delCT
CLNSRC	Breast Cancer Information Core (BRCA1)
CLNACC	RCV000031097.9, RCV000048107.6, RCV000162862.2, RCV000225762.2, RCV000473763.1,