rs80357877

minus

Geno	Mag	Summary
(-;GAAGATACTAG)	6	BRCA1 variant considered pathogenic for breast cancer
(GAAGATACTAG;GAAGATACTAG)	0	Normal

Make rs80357877(-;-)

Reference

GRCh38 38.1/141

Chromosome

17

Position

43092040

Gene

BRCA1

is a	snp
is	mentioned by
dbSNP	rs80357877
dbSNP (classic)	rs80357877
ClinGen	rs80357877
ebi	rs80357877
HLI	rs80357877
Exac	rs80357877
Gnomad	rs80357877
Varsome	rs80357877
LitVar	rs80357877
Map	rs80357877
PheGenI	rs80357877
Biobank	rs80357877
1000 genomes	rs80357877
hgdp	rs80357877
ensembl	rs80357877
geneview	rs80357877
scholar	rs80357877
google	rs80357877
pharmgkb	rs80357877
gwascentral	rs80357877
openSNP	rs80357877
23andMe	rs80357877
SNPshot	rs80357877
SNPdbe	rs80357877
MSV3d	rs80357877
GWAS Ctlg	rs80357877

Merged from

Rs80357910

Max Magnitude

6

rs80357877, also known as 3600del11, c.3481_3491delGAAGATACTAG and p.Glu1161_Ser1164?fs, is a variant in the BRCA1 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80357877(AGGAAGATACT;AGGAAGATACT) rs80357877(-;-)
Alt	rs80357877(AGGAAGATACT;AGGAAGATACT) rs80357877(-;-)
Reference	Rs80357877(GAAGATACTAG;GAAGATACTAG)
Significance	Pathogenic
Disease	Breast-ovarian cancer Hereditary breast and ovarian cancer syndrome Hereditary cancer-predisposing syndrome not provided
Variation	info
Gene	BRCA1
CLNDBN	Breast-ovarian cancer, familial 1 Hereditary breast and ovarian cancer syndrome Hereditary cancer-predisposing syndrome not provided
Reversed	1
HGVS	NC_000017.10:g.41244057_41244067delCTAGTATCTTC
CLNSRC	Breast Cancer Information Core (BRCA1) OMIM Allelic Variant
CLNACC	RCV000019254.15, RCV000048211.6, RCV000131815.4, RCV000159917.3,