rs80359352

plus

Geno	Mag	Summary
(-;ACAA)	6	BRCA2 variant considered pathogenic for breast cancer
(AAAC;AAAC)	0	common in clinvar
(ACAA;ACAA)	0	common in clinvar

Make rs80359352(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32337163

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359352
dbSNP (classic)	rs80359352
ClinGen	rs80359352
ebi	rs80359352
HLI	rs80359352
Exac	rs80359352
Gnomad	rs80359352
Varsome	rs80359352
LitVar	rs80359352
Map	rs80359352
PheGenI	rs80359352
Biobank	rs80359352
1000 genomes	rs80359352
hgdp	rs80359352
ensembl	rs80359352
geneview	rs80359352
scholar	rs80359352
google	rs80359352
pharmgkb	rs80359352
gwascentral	rs80359352
openSNP	rs80359352
23andMe	rs80359352
SNPshot	rs80359352
SNPdbe	rs80359352
MSV3d	rs80359352
GWAS Ctlg	rs80359352

Status

Merged into rs80359351

Max Magnitude

6

rs80359352, also known as 3036del4, c.2808_2811delACAA and p.Ala938ProfsX21, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk
Alt
Reference	Rs80359352(AAAC;AAAC)
Significance	Pathogenic
Disease	Breast-ovarian cancer Hereditary breast and ovarian cancer syndrome Hereditary cancer-predisposing syndrome not provided Breast-ovarian cancer not specified Breast cancer
Variation	info
Gene	BRCA2
CLNDBN	Breast-ovarian cancer, familial 2 Hereditary breast and ovarian cancer syndrome Hereditary cancer-predisposing syndrome not provided Breast-ovarian cancer, familial 1 not specified Breast cancer
Reversed	0
HGVS	NC_000013.10:g.32911300_32911303delACAA
CLNSRC	Breast Cancer Information Core (BRCA2) Inc. OMIM Allelic Variant
CLNACC	RCV000009907.8, RCV000044064.8, RCV000131102.4, RCV000160273.3, RCV000210161.1, RCV000238794.1, RCV000240755.1,