rs80359357

plus

Geno	Mag	Summary
(-;GA)	6	BRCA2 variant considered pathogenic for breast cancer
(AG;AG)	0	common in clinvar
(GA;GA)	0	common in clinvar

Make rs80359357(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32337191

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359357
dbSNP (classic)	rs80359357
ClinGen	rs80359357
ebi	rs80359357
HLI	rs80359357
Exac	rs80359357
Gnomad	rs80359357
Varsome	rs80359357
LitVar	rs80359357
Map	rs80359357
PheGenI	rs80359357
Biobank	rs80359357
1000 genomes	rs80359357
hgdp	rs80359357
ensembl	rs80359357
geneview	rs80359357
scholar	rs80359357
google	rs80359357
pharmgkb	rs80359357
gwascentral	rs80359357
openSNP	rs80359357
23andMe	rs80359357
SNPshot	rs80359357
SNPdbe	rs80359357
MSV3d	rs80359357
GWAS Ctlg	rs80359357

Max Magnitude

6

rs80359357, also known as 3064delGA, c.2836_2837delGA and p.Asp946Phefs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359357(-;-)
Alt	rs80359357(-;-)
Reference	Rs80359357(AG;AG)
Significance	Pathogenic
Disease	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer Hereditary cancer-predisposing syndrome
Variation	info
Gene	BRCA2
CLNDBN	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer, familial 2 Hereditary cancer-predisposing syndrome
Reversed	0
HGVS	NC_000013.10:g.32911328_32911329delGA
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000044071.5, RCV000113101.3, RCV000162914.2,