rs80359524

plus

Geno	Mag	Summary
(-;AT)	6	BRCA2 variant considered pathogenic for breast cancer
(AT;AT)	0	common in clinvar

Make rs80359524(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32339950

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359524
dbSNP (classic)	rs80359524
ClinGen	rs80359524
ebi	rs80359524
HLI	rs80359524
Exac	rs80359524
Gnomad	rs80359524
Varsome	rs80359524
LitVar	rs80359524
Map	rs80359524
PheGenI	rs80359524
Biobank	rs80359524
1000 genomes	rs80359524
hgdp	rs80359524
ensembl	rs80359524
geneview	rs80359524
scholar	rs80359524
google	rs80359524
pharmgkb	rs80359524
gwascentral	rs80359524
openSNP	rs80359524
23andMe	rs80359524
SNPshot	rs80359524
SNPdbe	rs80359524
MSV3d	rs80359524
GWAS Ctlg	rs80359524

Max Magnitude

6

rs80359524, also known as 5823delAT, c.5595_5596delAT and p.Ile1865_Phe1866IleTyrfs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359524(-;-)
Alt	rs80359524(-;-)
Reference	Rs80359524(AT;AT)
Significance	Pathogenic
Disease	Breast-ovarian cancer Familial cancer of breast Hereditary cancer-predisposing syndrome
Variation	info
Gene	BRCA2
CLNDBN	Breast-ovarian cancer, familial 2 Familial cancer of breast Hereditary cancer-predisposing syndrome
Reversed	0
HGVS	NC_000013.10:g.32914087_32914088delAT
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000031558.6, RCV000044690.2, RCV000219038.1,