rs80359680

Merged into

rs80359677

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(-;GA)	6	BRCA2 variant considered pathogenic for breast cancer
(AG;AG)	0	common in clinvar
(GA;GA)	0	common in clinvar

Make rs80359680(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32331015

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359680
dbSNP (classic)	rs80359680
ClinGen	rs80359680
ebi	rs80359680
HLI	rs80359680
Exac	rs80359680
Gnomad	rs80359680
Varsome	rs80359680
LitVar	rs80359680
Map	rs80359680
PheGenI	rs80359680
Biobank	rs80359680
1000 genomes	rs80359680
hgdp	rs80359680
ensembl	rs80359680
geneview	rs80359680
scholar	rs80359680
google	rs80359680
pharmgkb	rs80359680
gwascentral	rs80359680
openSNP	rs80359680
23andMe	rs80359680
SNPshot	rs80359680
SNPdbe	rs80359680
MSV3d	rs80359680
GWAS Ctlg	rs80359680

Status

Merged into rs80359677

Max Magnitude

6

rs80359680, also known as 1006delGA, c.778_779delGA and p.Glu260Serfs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk
Alt
Reference	Rs80359680(AG;AG)
Significance	Pathogenic
Disease	Breast-ovarian cancer not provided Hereditary cancer-predisposing syndrome Hereditary breast and ovarian cancer syndrome
Variation	info
Gene	BRCA2
CLNDBN	Breast-ovarian cancer, familial 2 not provided Hereditary cancer-predisposing syndrome Hereditary breast and ovarian cancer syndrome
Reversed	0
HGVS	NC_000013.10:g.32905152_32905153delGA
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000031701.6, RCV000045311.5, RCV000131854.3, RCV000203632.2,