rs8042374
From SNPedia
| May affect lung cancer risk |
| Orientation | plus |
| Stabilized | plus |
| Make rs8042374(A;A) |
| Make rs8042374(A;G) |
| Make rs8042374(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 15 |
| Position | 78615690 |
| Gene | CHRNA3 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs8042374 |
| dbSNP (classic) | rs8042374 |
| ClinGen | rs8042374 |
| ebi | rs8042374 |
| HLI | rs8042374 |
| Exac | rs8042374 |
| Gnomad | rs8042374 |
| Varsome | rs8042374 |
| LitVar | rs8042374 |
| Map | rs8042374 |
| PheGenI | rs8042374 |
| Biobank | rs8042374 |
| 1000 genomes | rs8042374 |
| hgdp | rs8042374 |
| ensembl | rs8042374 |
| geneview | rs8042374 |
| scholar | rs8042374 |
| rs8042374 | |
| pharmgkb | rs8042374 |
| gwascentral | rs8042374 |
| openSNP | rs8042374 |
| 23andMe | rs8042374 |
| SNPshot | rs8042374 |
| SNPdbe | rs8042374 |
| MSV3d | rs8042374 |
| GWAS Ctlg | rs8042374 |
| GMAF | 0.4385 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
[PMID 18978787
] lung cancer rs8042374 P = 7.75 x 10(-12)
[PMID 18519524] Variants in nicotinic receptors and risk for nicotine dependence.
[PMID 19654303] Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study.
[PMID 19706762] The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans.
[PMID 19955392] Role of 5p15.33 (TERT-CLPTM1L), 6p21.33 and 15q25.1 (CHRNA5-CHRNA3) variation and lung cancer risk in never-smokers.
