rs8055236
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 0 | |
| (G;G) | 1.7 | common, but 2.2x higher risk for heart disease |
| (G;T) | 1.7 | 1.9x risk for heart disease |
| (T;T) | 0 | normal |
| Reference | GRCh38 38.1/141 |
| Chromosome | 16 |
| Position | 83178793 |
| Gene | CDH13 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs8055236 |
| dbSNP (classic) | rs8055236 |
| ClinGen | rs8055236 |
| ebi | rs8055236 |
| HLI | rs8055236 |
| Exac | rs8055236 |
| Gnomad | rs8055236 |
| Varsome | rs8055236 |
| LitVar | rs8055236 |
| Map | rs8055236 |
| PheGenI | rs8055236 |
| Biobank | rs8055236 |
| 1000 genomes | rs8055236 |
| hgdp | rs8055236 |
| ensembl | rs8055236 |
| geneview | rs8055236 |
| scholar | rs8055236 |
| rs8055236 | |
| pharmgkb | rs8055236 |
| gwascentral | rs8055236 |
| openSNP | rs8055236 |
| 23andMe | rs8055236 |
| SNPshot | rs8055236 |
| SNPdbe | rs8055236 |
| MSV3d | rs8055236 |
| GWAS Ctlg | rs8055236 |
| GMAF | 0.2447 |
| Max Magnitude | 1.7 |
| ? | (G;G) (G;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs8055236 has been reported in a large study to be associated with heart disease, in particular, coronary artery disease.
The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with heterozygotes is 1.91 (CI 1.33-2.74), and for homozygotes, 2.23 (CI 1.56-3.17). [PMID 17554300
]
| GWAS | |
|---|---|
| SNP | rs8055236 |
| PubMedID | [PMID 17554300]
|
| Condition | Coronary disease |
| Gene | NR |
| Risk Allele | G |
| pValue | 6.00E-006 |
| OR | 1.91 |
| 95% CI | 1.33-2.74 |
[PMID 19956433] Genetics of coronary artery disease: focus on genome-wide association studies.
[PMID 20017983] Evaluation of population impact of candidate polymorphisms for coronary heart disease in the Framingham Heart Study Offspring Cohort.
