rs806377
| Orientation | plus |
| Stabilized | plus |
| Make rs806377(C;C) |
| Make rs806377(C;T) |
| Make rs806377(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 6 |
| Position | 88149004 |
| Gene | CNR1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs806377 |
| dbSNP (classic) | rs806377 |
| ClinGen | rs806377 |
| ebi | rs806377 |
| HLI | rs806377 |
| Exac | rs806377 |
| Gnomad | rs806377 |
| Varsome | rs806377 |
| LitVar | rs806377 |
| Map | rs806377 |
| PheGenI | rs806377 |
| Biobank | rs806377 |
| 1000 genomes | rs806377 |
| hgdp | rs806377 |
| ensembl | rs806377 |
| geneview | rs806377 |
| scholar | rs806377 |
| rs806377 | |
| pharmgkb | rs806377 |
| gwascentral | rs806377 |
| openSNP | rs806377 |
| 23andMe | rs806377 |
| SNPshot | rs806377 |
| SNPdbe | rs806377 |
| MSV3d | rs806377 |
| GWAS Ctlg | rs806377 |
| GMAF | 0.4775 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs806377(C) together with rs6454674(G) make up a haplotype associated (p=0.008) with higher risk of ADHD. In addition, the haplotype was more associated (p=0.03) with ADHD in males than in females with the risk haplotype. [PMID 18213623
]
[PMID 16917946
] Cannabis receptor haplotype associated with fewer cannabis dependence symptoms in adolescents.
[PMID 19016476
] Evidence for association between polymorphisms in the cannabinoid receptor 1 (CNR1) gene and cannabis dependence.
[PMID 19052543
] Interaction between two independent CNR1 variants increases risk for cocaine dependence in European Americans: a replication study in family-based sample and population-based sample.
[PMID 19335651
] Candidate genes for cannabis use disorders: findings, challenges and directions.
[PMID 19443135
] The association between cannabinoid receptor 1 gene (CNR1) and cannabis dependence symptoms in adolescents and young adults.
[PMID 21714860
] Variation in the human cannabinoid receptor CNR1 gene modulates gaze duration for happy faces. (C;C) associated with the highest striatal response is also associated with the longest gaze duration for happy faces.
[PMID 23407780] Screening genetic variability at the CNR1 gene in both major depression etiology and clinical response to citalopram treatment.
[PMID 23422373] CNR1 gene and risk of the metabolic syndrome in patients with schizophrenia.
