rs9268839
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;G) | 2 | 2x increase in rheumatoid arthritis risk (in Caucasians) |
| (G;G) | 2.9 | Moderately (~4x) increased rheumatoid arthritis risk (in Caucasians) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 6 |
| Position | 32460995 |
| Gene | HLA-DRB9 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs9268839 |
| dbSNP (classic) | rs9268839 |
| ClinGen | rs9268839 |
| ebi | rs9268839 |
| HLI | rs9268839 |
| Exac | rs9268839 |
| Gnomad | rs9268839 |
| Varsome | rs9268839 |
| LitVar | rs9268839 |
| Map | rs9268839 |
| PheGenI | rs9268839 |
| Biobank | rs9268839 |
| 1000 genomes | rs9268839 |
| hgdp | rs9268839 |
| ensembl | rs9268839 |
| geneview | rs9268839 |
| scholar | rs9268839 |
| rs9268839 | |
| pharmgkb | rs9268839 |
| gwascentral | rs9268839 |
| openSNP | rs9268839 |
| 23andMe | rs9268839 |
| SNPshot | rs9268839 |
| SNPdbe | rs9268839 |
| MSV3d | rs9268839 |
| GWAS Ctlg | rs9268839 |
| GMAF | 0.377 |
| Max Magnitude | 2.9 |
[PMID 24390342
] rs9268839(G) was the variant most strongly associated in Europeans with risk for rheumatoid arthritis in this GWAS study of ~30,000 patients (OR 2.47, CI: 2.39-2.55, p = 1.5 × 10−e300).
[PMID 23151485] Association of ANXA11 genetic variation with sarcoidosis in African Americans and European Americans
| GWAS snp | |
|---|---|
| PMID | [PMID 24390342]
|
| Trait | Rheumatoid arthritis |
| Title | Genetics of rheumatoid arthritis contributes to biology and drug discovery. |
| Risk Allele | G |
| P-val | 1E-250 |
| Odds Ratio | 2.47 [2.39-2.55] |
