| Rs9292777
|
| PubMed
|
[PMID 17447842 ]
|
| Affy Probeset
|
SNP_A-2211129
|
| Affy Orientation
|
same
|
| On GW 5.0
|
1
|
| Alleles A/B
|
C/T
|
| Ancestral
|
C
|
| Population
|
EU
|
| Allele
|
T
|
| Case Freq.
|
0.68
|
| Control Freq.
|
0.59
|
| Odds Ratio Het
|
|
| Odds Ratio Hom
|
|
| Odds Ratio All
|
1.46
|
| Disease
|
Crohn's disease (CD)
|
rs9292777 is in linkage disequilibrium with a polymorphism that increases susceptibility to Crohn's disease 1.46 times for carriers of the T allele [PMID 17447842]
| GWAS snp
|
| PMID
|
[PMID 17554261]
|
| Trait
|
Crohn's disease
|
| Title
|
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility
|
| Risk Allele
|
|
| P-val
|
2.9999999999999998E-18
|
| Odds Ratio
|
1.34 [1.20-1.50]
|
[PMID 19953089] Differences in genetic background between active smokers, passive smokers, and non-smokers with Crohn's disease
| GWAS snp
|
| PMID
|
[PMID 22570697]
|
| Trait
|
|
| Title
|
Genome-wide association study of multiple sclerosis confirms a novel locus at 5p13.1.
|
| Risk Allele
|
T
|
| P-val
|
1E-9
|
| Odds Ratio
|
1.1900 None
|
| GWAS snp
|
| PMID
|
[PMID 22412388]
|
| Trait
|
|
| Title
|
A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.
|
| Risk Allele
|
T
|
| P-val
|
2E-11
|
| Odds Ratio
|
1.3700 None
|
[PMID 18438406] Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease.
[PMID 19140132] Unbiased estimation of odds ratios: combining genomewide association scans with replication studies.
]
