rs944289
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | |
| (C;T) | 2.1 | 1.3x increased thyroid cancer risk |
| (T;T) | 2.2 | 1.69x increased thyroid cancer risk |
| Reference | GRCh38 38.1/141 |
| Chromosome | 14 |
| Position | 36180040 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs944289 |
| dbSNP (classic) | rs944289 |
| ClinGen | rs944289 |
| ebi | rs944289 |
| HLI | rs944289 |
| Exac | rs944289 |
| Gnomad | rs944289 |
| Varsome | rs944289 |
| LitVar | rs944289 |
| Map | rs944289 |
| PheGenI | rs944289 |
| Biobank | rs944289 |
| 1000 genomes | rs944289 |
| hgdp | rs944289 |
| ensembl | rs944289 |
| geneview | rs944289 |
| scholar | rs944289 |
| rs944289 | |
| pharmgkb | rs944289 |
| gwascentral | rs944289 |
| openSNP | rs944289 |
| 23andMe | rs944289 |
| SNPshot | rs944289 |
| SNPdbe | rs944289 |
| MSV3d | rs944289 |
| GWAS Ctlg | rs944289 |
| GMAF | 0.4288 |
| Max Magnitude | 2.2 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
[PMID 19198613
] Each A at rs965513 increased the odds of thyroid cancer by 1.75 times. Each T at rs944289 increased the odds of thyroid cancer by 1.37 times.
A genoset, Gs137, has also been created in SNPedia to represent the increased risk reported for carriers of both variants.
See also: 23andMe blog
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[PMID 32104174] Association of rs944289, rs965513, and rs1443434 in TITF1/TITF2 with Risks of Papillary Thyroid Carcinoma and with Nodular Goiter in Northern Chinese Han Populations.
