rs9469220
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 1.5x risk of Crohn's disease | |
| (A;G) | 1.1x risk of Crohn's disease | |
| (C;C) | 0 | |
| (G;G) | 0 | normal |
| Reference | GRCh38 38.1/141 |
| Chromosome | 6 |
| Position | 32690533 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs9469220 |
| dbSNP (classic) | rs9469220 |
| ClinGen | rs9469220 |
| ebi | rs9469220 |
| HLI | rs9469220 |
| Exac | rs9469220 |
| Gnomad | rs9469220 |
| Varsome | rs9469220 |
| LitVar | rs9469220 |
| Map | rs9469220 |
| PheGenI | rs9469220 |
| Biobank | rs9469220 |
| 1000 genomes | rs9469220 |
| hgdp | rs9469220 |
| ensembl | rs9469220 |
| geneview | rs9469220 |
| scholar | rs9469220 |
| rs9469220 | |
| pharmgkb | rs9469220 |
| gwascentral | rs9469220 |
| openSNP | rs9469220 |
| 23andMe | rs9469220 |
| SNPshot | rs9469220 |
| SNPdbe | rs9469220 |
| MSV3d | rs9469220 |
| GWAS Ctlg | rs9469220 |
| GMAF | 0.4192 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
rs9469220 has been reported in a large study to be associated with Crohn's disease.
The risk allele (oriented to the dbSNP entry) is (A); the odds ratio associated with heterozygotes is 1.14 (CI 0.98-1.32), and for homozygotes, 1.52 (CI 1.28-1.79). [PMID 17554300
]
| GWAS | |
|---|---|
| SNP | rs9469220 |
| PubMedID | [PMID 17554300]
|
| Condition | Crohn's disease |
| Gene | NR |
| Risk Allele | A |
| pValue | 2.00E-006 |
| OR | 1.14 |
| 95% CI | 0.98-1.32 |
[PMID 22615847] Association Analysis of the Extended MHC Region in Celiac Disease Implicates Multiple Independent Susceptibility Loci
[PMID 17660530] Risk alleles for multiple sclerosis identified by a genomewide study.
[PMID 20369022] Candidate causal regulatory effects by integration of expression QTLs with complex trait genetic associations.
[PMID 20546594] An application of Random Forests to a genome-wide association dataset: methodological considerations & new findings.
| GWAS snp | |
|---|---|
| PMID | [PMID 23146381]
|
| Trait | IgE levels |
| Title | A meta-analysis of genome-wide association studies for serum total IgE in diverse study populations. |
| Risk Allele | G |
| P-val | 2E-7 |
| Odds Ratio | .09 [0.05-0.12] unit decrease |
[PMID 24352087] Candidate genes involved in beneficial or adverse responses to commonly eaten brassica vegetables in a New Zealand Crohn's disease cohort
[PMID 25308886] Functional relevance for multiple sclerosis-associated genetic variants
